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FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis
Cancer cells balance with the equilibrium of cell death and growth to expand and metastasize. The activity of mammalian sterile20-like kinases (MST1/2) has been linked to apoptosis and tumor suppression via YAP/Hippo pathway-independent and -dependent mechanisms. Using a kinase substrate screen, we...
Autores principales: | Turunen, S. Pauliina, von Nandelstadh, Pernilla, Öhman, Tiina, Gucciardo, Erika, Seashore-Ludlow, Brinton, Martins, Beatriz, Rantanen, Ville, Li, Huini, Höpfner, Katrin, Östling, Päivi, Varjosalo, Markku, Lehti, Kaisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224384/ https://www.ncbi.nlm.nih.gov/pubmed/30903103 http://dx.doi.org/10.1038/s41418-019-0321-x |
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