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FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis

Cancer cells balance with the equilibrium of cell death and growth to expand and metastasize. The activity of mammalian sterile20-like kinases (MST1/2) has been linked to apoptosis and tumor suppression via YAP/Hippo pathway-independent and -dependent mechanisms. Using a kinase substrate screen, we...

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Detalles Bibliográficos
Autores principales: Turunen, S. Pauliina, von Nandelstadh, Pernilla, Öhman, Tiina, Gucciardo, Erika, Seashore-Ludlow, Brinton, Martins, Beatriz, Rantanen, Ville, Li, Huini, Höpfner, Katrin, Östling, Päivi, Varjosalo, Markku, Lehti, Kaisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224384/
https://www.ncbi.nlm.nih.gov/pubmed/30903103
http://dx.doi.org/10.1038/s41418-019-0321-x

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