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The Effectiveness of Medical Prophylactic Treatment on Vestibular Migraine and Its Effect on the Quality Of Life

OBJECTIVES: The aim of the present study was to determine the efficacy of propranolol treatment in patients with vestibular migraine by the Visual Analog Scale, Dizziness Handicap Inventory (DHI), Vertigo Symptom Scale, and Vestibular Disorders Activities of Daily Living Scale (VADL) and its effect...

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Autores principales: Çelik, Onur, Toker, Gökçe Tanyeri, Eskiizmir, Görkem, İncesulu, Armağan, Süyür, Nevin Şahin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The European Academy of Otology and Neurotology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224423/
https://www.ncbi.nlm.nih.gov/pubmed/31347507
http://dx.doi.org/10.5152/iao.2019.6522
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author Çelik, Onur
Toker, Gökçe Tanyeri
Eskiizmir, Görkem
İncesulu, Armağan
Süyür, Nevin Şahin
author_facet Çelik, Onur
Toker, Gökçe Tanyeri
Eskiizmir, Görkem
İncesulu, Armağan
Süyür, Nevin Şahin
author_sort Çelik, Onur
collection PubMed
description OBJECTIVES: The aim of the present study was to determine the efficacy of propranolol treatment in patients with vestibular migraine by the Visual Analog Scale, Dizziness Handicap Inventory (DHI), Vertigo Symptom Scale, and Vestibular Disorders Activities of Daily Living Scale (VADL) and its effect on the quality of life. MATERIALS AND METHODS: The study population consisted of 38 patients with vertigo/dizziness who underwent routine evaluation and vestibular examinations, were diagnosed with definitive vestibular migraine, and received the same medical treatment protocol (propranolol). The questionnaires and scales that were applied to the patients before and after treatment were evaluated. The results were evaluated with 95% confidence interval, and p<0.05 was accepted as statistically significant. RESULTS: The mean age of the patients was 47.55 (18–75) years, and 27 (71%) patients were female, and 11 (29%) were male. The mean total scores of the DHI before and after treatment were 50.21±22.39 (range: 8–92) and 9.31±9.86 (range: 0–58), respectively (p<0.001). The degree of disability after treatment was low in all patients (p<0.001). The total scores of the VADL before and after treatment were 186.63±79.65 (range: 32–280) and 55.52±51.89 (range: 28–273), respectively (p<0.001). There was no correlation between these two scales (p=0.235). CONCLUSION: To our knowledge, this is the first study to evaluate both the efficacy of propranolol treatment and its effects on the quality of life in vestibular migraine. The severity, frequency, and number of attacks and disability scores were reduced, and the quality of life was improved in patients with vestibular migraine with propranolol treatment.
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spelling pubmed-72244232020-05-15 The Effectiveness of Medical Prophylactic Treatment on Vestibular Migraine and Its Effect on the Quality Of Life Çelik, Onur Toker, Gökçe Tanyeri Eskiizmir, Görkem İncesulu, Armağan Süyür, Nevin Şahin J Int Adv Otol Original Article OBJECTIVES: The aim of the present study was to determine the efficacy of propranolol treatment in patients with vestibular migraine by the Visual Analog Scale, Dizziness Handicap Inventory (DHI), Vertigo Symptom Scale, and Vestibular Disorders Activities of Daily Living Scale (VADL) and its effect on the quality of life. MATERIALS AND METHODS: The study population consisted of 38 patients with vertigo/dizziness who underwent routine evaluation and vestibular examinations, were diagnosed with definitive vestibular migraine, and received the same medical treatment protocol (propranolol). The questionnaires and scales that were applied to the patients before and after treatment were evaluated. The results were evaluated with 95% confidence interval, and p<0.05 was accepted as statistically significant. RESULTS: The mean age of the patients was 47.55 (18–75) years, and 27 (71%) patients were female, and 11 (29%) were male. The mean total scores of the DHI before and after treatment were 50.21±22.39 (range: 8–92) and 9.31±9.86 (range: 0–58), respectively (p<0.001). The degree of disability after treatment was low in all patients (p<0.001). The total scores of the VADL before and after treatment were 186.63±79.65 (range: 32–280) and 55.52±51.89 (range: 28–273), respectively (p<0.001). There was no correlation between these two scales (p=0.235). CONCLUSION: To our knowledge, this is the first study to evaluate both the efficacy of propranolol treatment and its effects on the quality of life in vestibular migraine. The severity, frequency, and number of attacks and disability scores were reduced, and the quality of life was improved in patients with vestibular migraine with propranolol treatment. The European Academy of Otology and Neurotology 2020-04 2019-07-24 /pmc/articles/PMC7224423/ /pubmed/31347507 http://dx.doi.org/10.5152/iao.2019.6522 Text en © Copyright 2020 The European Academy of Otology and Neurotology https://creativecommons.org/licenses/by-nc/4.0/Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
spellingShingle Original Article
Çelik, Onur
Toker, Gökçe Tanyeri
Eskiizmir, Görkem
İncesulu, Armağan
Süyür, Nevin Şahin
The Effectiveness of Medical Prophylactic Treatment on Vestibular Migraine and Its Effect on the Quality Of Life
title The Effectiveness of Medical Prophylactic Treatment on Vestibular Migraine and Its Effect on the Quality Of Life
title_full The Effectiveness of Medical Prophylactic Treatment on Vestibular Migraine and Its Effect on the Quality Of Life
title_fullStr The Effectiveness of Medical Prophylactic Treatment on Vestibular Migraine and Its Effect on the Quality Of Life
title_full_unstemmed The Effectiveness of Medical Prophylactic Treatment on Vestibular Migraine and Its Effect on the Quality Of Life
title_short The Effectiveness of Medical Prophylactic Treatment on Vestibular Migraine and Its Effect on the Quality Of Life
title_sort effectiveness of medical prophylactic treatment on vestibular migraine and its effect on the quality of life
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224423/
https://www.ncbi.nlm.nih.gov/pubmed/31347507
http://dx.doi.org/10.5152/iao.2019.6522
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