Cargando…
Novel malaria antigen Plasmodium yoelii E140 induces antibody-mediated sterile protection in mice against malaria challenge
Only a small fraction of the antigens expressed by malaria parasites have been evaluated as vaccine candidates. A successful malaria subunit vaccine will likely require multiple antigenic targets to achieve broad protection with high protective efficacy. Here we describe protective efficacy of a nov...
Autores principales: | Smith, Emily C., Limbach, Keith J., Rangel, Nonenipha, Oda, Kyosuke, Bolton, Jessica S., Du, Mengyan, Gowda, Kalpana, Wang, Jianyang, Moch, J. Kathleen, Sonawane, Sharvari, Velasco, Rachel, Belmonte, Arnel, Danner, Rebecca, Lumsden, Joanne M., Patterson, Noelle B., Sedegah, Martha, Hollingdale, Michael R., Richie, Thomas L., Sacci, John B., Villasante, Eileen D., Aguiar, Joao C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224506/ https://www.ncbi.nlm.nih.gov/pubmed/32407410 http://dx.doi.org/10.1371/journal.pone.0232234 |
Ejemplares similares
-
New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model
por: Limbach, Keith, et al.
Publicado: (2017) -
Identification of two new protective pre-erythrocytic malaria vaccine antigen candidates
por: Limbach, Keith, et al.
Publicado: (2011) -
Controlled Human Malaria Infection (CHMI) differentially affects cell-mediated and antibody responses to CSP and AMA1 induced by adenovirus vaccines with and without DNA-priming
por: Sedegah, Martha, et al.
Publicado: (2015) -
A three-antigen Plasmodium falciparum DNA prime—Adenovirus boost malaria vaccine regimen is superior to a two-antigen regimen and protects against controlled human malaria infection in healthy malaria-naïve adults
por: Sklar, Marvin J., et al.
Publicado: (2021) -
IMRAS—Immunization with radiation-attenuated Plasmodium falciparum sporozoites by mosquito bite: Cellular immunity to sporozoites, CSP, AMA1, TRAP and CelTOS
por: Sedegah, Martha, et al.
Publicado: (2021)