Rev-erbα heterozygosity produces a dose-dependent phenotypic advantage in mice

Numerous mutational studies have demonstrated that circadian clock proteins regulate behavior and metabolism. Nr1d1(Rev-erbα) is a key regulator of circadian gene expression and a pleiotropic regulator of skeletal muscle homeostasis and lipid metabolism. Loss of Rev-erbα expression induces muscular...

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Detalles Bibliográficos
Autores principales: Welch, Ryan D., Billon, Cyrielle, Kameric, Amina, Burris, Thomas P., Flaveny, Colin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224546/
https://www.ncbi.nlm.nih.gov/pubmed/32407314
http://dx.doi.org/10.1371/journal.pone.0227720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224546/
https://www.ncbi.nlm.nih.gov/pubmed/32407314
http://dx.doi.org/10.1371/journal.pone.0227720

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