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Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation
Chitinases are important enzymes that contribute to the generation of carbon and nitrogen from chitin, a long chain polymer of N-acetylglucosamine that is abundant in insects, fungi, invertebrates and fish. Although mammals do not produce chitin, chitinases have been identified in bacteria that are...
Autores principales: | Rehman, Saima, Grigoryeva, Lubov S., Richardson, Katherine H., Corsini, Paula, White, Richard C., Shaw, Rosie, Portlock, Theo J., Dorgan, Benjamin, Zanjani, Zeinab S., Fornili, Arianna, Cianciotto, Nicholas P., Garnett, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224574/ https://www.ncbi.nlm.nih.gov/pubmed/32365117 http://dx.doi.org/10.1371/journal.ppat.1008342 |
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