In Vitro and In Vivo Validation of EP2-Receptor Agonism to Selectively Achieve Inhibition of Mast Cell Activity

PURPOSE: Agonism of the prostaglandin E2 receptor, E-prostanoid receptor 2 (EP2), may represent an alternative protective mechanism in mast cell (MC)-mediated diseases. Previous studies have suggested that activation of the MC EP2 receptor prevents pathological changes in the murine models of allerg...

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Detalles Bibliográficos
Autores principales: Plaza, Judith, Torres, Rosa, Urbano, Adrián, Picado, César, de Mora, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225001/
https://www.ncbi.nlm.nih.gov/pubmed/32400135
http://dx.doi.org/10.4168/aair.2020.12.4.712

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