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Cleavage of Desmosomal Cadherins Promotes γ-Catenin Degradation and Benefits Wnt Signaling in Coxsackievirus B3-Induced Destruction of Cardiomyocytes

Coxsackievirus B3 (CVB3) is the primary etiologic agent of viral myocarditis, a major heart disease that occurs predominantly in children and young adolescents. In the heart, intercalated disks (ICD) are important structural formations that connect adjacent cardiomyocytes to maintain cardiac archite...

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Detalles Bibliográficos
Autores principales: Zhao, Guangze, Zhang, Huifang M., Qiu, Ye, Ye, Xin, Yang, Decheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225294/
https://www.ncbi.nlm.nih.gov/pubmed/32457708
http://dx.doi.org/10.3389/fmicb.2020.00767