Cargando…

PE_PGRS31-S100A9 Interaction Promotes Mycobacterial Survival in Macrophages Through the Regulation of NF-κB-TNF-α Signaling and Arachidonic Acid Metabolism

Mycobacterium tuberculosis (M. tb) evades the surveillance of immune responses for survival in macrophages. However, the precise mechanism and toxins/proteins encoded by M. tb involved in the bacterial escape remain elusive. The function of Rv1768 protein (also referred to as PE_PGRS31, belonging to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Sheng, Xie, Yan, Luo, Wei, Dou, Yafeng, Xiong, Huan, Xiao, Zhen, Zhang, Xiao-Lian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225313/ https://www.ncbi.nlm.nih.gov/pubmed/32457723 http://dx.doi.org/10.3389/fmicb.2020.00845

Ejemplares similares

Mycobacterium tuberculosis PE_PGRS20 and PE_PGRS47 Proteins Inhibit Autophagy by Interaction with Rab1A
por: Strong, Emily J., et al.
Publicado: (2021)

Functional Dissection of the PE Domain Responsible for Translocation of PE_PGRS33 across the Mycobacterial Cell Wall
por: Cascioferro, Alessandro, et al.
Publicado: (2011)

A glycine-rich PE_PGRS protein governs mycobacterial actin-based motility
por: Hill, Norbert S., et al.
Publicado: (2022)

Mycobacterial PE_PGRS Proteins Contain Calcium-Binding Motifs with Parallel β-roll Folds
por: Bachhawat, Nandita, et al.
Publicado: (2007)

Design of a Multi-Epitope Vaccine against Tuberculosis from Mycobacterium tuberculosis PE_PGRS49 and PE_PGRS56 Proteins by Reverse Vaccinology
por: Ruaro-Moreno, Maritriny, et al.
Publicado: (2023)

Impact of Protein Domains on PE_PGRS30 Polar Localization in Mycobacteria
por: De Maio, Flavio, et al.
Publicado: (2014)

Computational analysis and prediction of PE_PGRS proteins using machine learning
por: Li, Fuyi, et al.
Publicado: (2022)

Structural Basis of PE_PGRS Polymorphism, a Tool for Functional Modulation
por: Kramarska, Eliza, et al.
Publicado: (2023)

Mycobacterial protein PE_PGRS30 induces macrophage apoptosis through prohibitin 2 mitochondrial function interference
por: Matsumura, Kazunori, et al.
Publicado: (2023)

The PGRS Domain from PE_PGRS33 of Mycobacterium tuberculosis is Target of Humoral Immune Response in Mice and Humans
por: Cohen, Ingrid, et al.
Publicado: (2014)

Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis
por: Camassa, Serena, et al.
Publicado: (2017)

Sequence Diversity in the pe_pgrs Genes of Mycobacterium tuberculosis Is Independent of Human T Cell Recognition
por: Copin, Richard, et al.
Publicado: (2014)

PE_PGRS33 Contributes to Mycobacterium tuberculosis Entry in Macrophages through Interaction with TLR2
por: Palucci, Ivana, et al.
Publicado: (2016)

PE_PGRS38 Interaction With HAUSP Downregulates Antimycobacterial Host Defense via TRAF6
por: Kim, Jae-Sung, et al.
Publicado: (2022)

The Mycobacterium tuberculosis PE_PGRS Protein Family Acts as an Immunological Decoy to Subvert Host Immune Response
por: Sharma, Tarina, et al.
Publicado: (2022)

Evolution of Smooth Tubercle Bacilli PE and PE_PGRS Genes: Evidence for a Prominent Role of Recombination and Imprint of Positive Selection
por: Namouchi, Amine, et al.
Publicado: (2013)

PE_PGRS proteins of Mycobacterium tuberculosis: A specialized molecular task force at the forefront of host–pathogen interaction
por: De Maio, Flavio, et al.
Publicado: (2020)

PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response
por: Kramarska, Eliza, et al.
Publicado: (2021)

Mycobacterium tuberculosis PE_PGRS19 Induces Pyroptosis through a Non-Classical Caspase-11/GSDMD Pathway in Macrophages
por: Qian, Jianing, et al.
Publicado: (2022)

The PGRS Domain of Mycobacterium tuberculosis PE_PGRS Protein Rv0297 Is Involved in Endoplasmic Reticulum Stress-Mediated Apoptosis through Toll-Like Receptor 4
por: Grover, Sonam, et al.
Publicado: (2018)

Insights into the evolutionary history of tubercle bacilli as disclosed by genetic rearrangements within a PE_PGRS duplicated gene pair
por: Karboul, Anis, et al.
Publicado: (2006)

Crystal structure of a putative aspartic proteinase domain of the Mycobacterium tuberculosis cell surface antigen PE_PGRS16()
por: Barathy, Deivanayaga V., et al.
Publicado: (2013)

Computational evaluation of anticipated PE_PGRS39 protein involvement in host–pathogen interplay and its integration into vaccine development
por: Patni, Khyati, et al.
Publicado: (2021)

Biochemical characterization of PE_PGRS61 family protein of Mycobacterium tuberculosis H(37)Rv reveals the binding ability to fibronectin
por: Monu,, et al.
Publicado: (2016)

PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction between M. tuberculosis and host cells
por: De Maio, Flavio, et al.
Publicado: (2021)

Reverse vaccinology approach to design a multi-epitope vaccine construct based on the Mycobacterium tuberculosis biomarker PE_PGRS17
por: Moodley, Avanthi, et al.
Publicado: (2022)

Codon Optimization, Soluble Expression and Purification of PE_PGRS45 Gene from Mycobacterium tuberculosis and Preparation of Its Polyclonal Antibody Protein
por: Xu, Tao, et al.
Publicado: (2021)

Mycobacterium tuberculosis PE_PGRS41 Enhances the Intracellular Survival of M. smegmatis within Macrophages Via Blocking Innate Immunity and Inhibition of Host Defense
por: Deng, Wanyan, et al.
Publicado: (2017)

RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection
por: Ates, Louis S., et al.
Publicado: (2018)

A novel class of antimicrobial drugs selectively targets a Mycobacterium tuberculosis PE-PGRS protein
por: Seo, Hoonhee, et al.
Publicado: (2022)

Immune Differentiation Regulator p100 Tunes NF-κB Responses to TNF
por: Chatterjee, Budhaditya, et al.
Publicado: (2019)

Mycobacterial PE/PPE Proteins at the Host-Pathogen Interface
por: Sampson, Samantha L.
Publicado: (2011)

miR-708 Negatively Regulates TNFα/IL-1β Signaling by Suppressing NF-κB and Arachidonic Acid Pathways
por: Monteleone, Nicholas J., et al.
Publicado: (2021)

PGRS domain structures: Doomed to sail the mycomembrane
por: Berisio, Rita, et al.
Publicado: (2022)

Host MKRN1-Mediated Mycobacterial PPE Protein Ubiquitination Suppresses Innate Immune Response
por: Dou, Yafeng, et al.
Publicado: (2022)

Total Flavonoids of Rhizoma Drynariae Treat Osteoarthritis by Inhibiting Arachidonic Acid Metabolites Through AMPK/NFκB Pathway
por: Chen, Guang-Yao, et al.
Publicado: (2023)

New insights into the mycobacterial PE and PPE proteins provide a framework for future research
por: Ates, Louis S.
Publicado: (2019)

Conserved Immune Recognition Hierarchy of Mycobacterial PE/PPE Proteins during Infection in Natural Hosts
por: Vordermeier, H. Martin, et al.
Publicado: (2012)

NF-κB-dependent miR-31/155 biogenesis is essential for TNF-α-induced impairment of endothelial progenitor cell function
por: Kim, Ji-Hee, et al.
Publicado: (2020)

Synthesis, Characterization, and Encapsulation of Novel Plant Growth Regulators (PGRs) in Biopolymer Matrices
por: Vlahoviček-Kahlina, Kristina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9eo13ibalr4jqr8ri88rs0nqkk