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Using Genetic Risk Score Approaches to Infer Whether an Environmental Factor Attenuates or Exacerbates the Adverse Influence of a Candidate Gene
Some candidate genes have been robustly reported to be associated with complex traits, such as the fat mass and obesity-associated (FTO) gene on body mass index (BMI), and the fibroblast growth factor 5 (FGF5) gene on blood pressure levels. It is of interest to know whether an environmental factor (...
Autores principales: | Lin, Wan-Yu, Lin, Yu-Shun, Chan, Chang-Chuan, Liu, Yu-Li, Tsai, Shih-Jen, Kuo, Po-Hsiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225361/ https://www.ncbi.nlm.nih.gov/pubmed/32457790 http://dx.doi.org/10.3389/fgene.2020.00331 |
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