Reversal of Hypoxic Pulmonary Hypertension by Hypoxia-Inducible Overexpression of Angiotensin-(1-7) in Pulmonary Endothelial Cells

Hypoxia-induced pulmonary vascular constriction and structure remodeling are the main causes of hypoxic pulmonary hypertension. In the present study, an adeno-associated virus vector, containing Tie2 promoter and hypoxia response elements, was designed and named HTSFcAng(1-7). Its targeting, hypoxic...

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Detalles Bibliográficos
Autores principales: Liu, Man-Ling, Xing, Shu-Juan, Liang, Xiao-Qing, Luo, Ying, Zhang, Bo, Li, Zhi-Chao, Dong, Ming-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225382/
https://www.ncbi.nlm.nih.gov/pubmed/32426413
http://dx.doi.org/10.1016/j.omtm.2020.04.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225382/
https://www.ncbi.nlm.nih.gov/pubmed/32426413
http://dx.doi.org/10.1016/j.omtm.2020.04.008

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