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Body fat percentage in adolescents with phenylketonuria and associated factors

OBJECTIVE: To evaluate the percentage of body fat (% BF) in adolescents with PKU and to relate it to protein consumption, physical activity level, body mass index (BMI), sexual maturity and metabolic control. METHOD: This is a cross-sectional study conducted with 94 adolescents between 10 and 20 yea...

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Autores principales: Camatta, Giovanna Caliman, Kanufre, Viviane de Cássia, Alves, Michelle Rosa Andrade, Soares, Rosângelis Del Lama, Norton, Rocksane de Carvalho, de Aguiar, Marcos José Burle, Starling, Ana Lúcia Pimenta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225391/
https://www.ncbi.nlm.nih.gov/pubmed/32426233
http://dx.doi.org/10.1016/j.ymgmr.2020.100595
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author Camatta, Giovanna Caliman
Kanufre, Viviane de Cássia
Alves, Michelle Rosa Andrade
Soares, Rosângelis Del Lama
Norton, Rocksane de Carvalho
de Aguiar, Marcos José Burle
Starling, Ana Lúcia Pimenta
author_facet Camatta, Giovanna Caliman
Kanufre, Viviane de Cássia
Alves, Michelle Rosa Andrade
Soares, Rosângelis Del Lama
Norton, Rocksane de Carvalho
de Aguiar, Marcos José Burle
Starling, Ana Lúcia Pimenta
author_sort Camatta, Giovanna Caliman
collection PubMed
description OBJECTIVE: To evaluate the percentage of body fat (% BF) in adolescents with PKU and to relate it to protein consumption, physical activity level, body mass index (BMI), sexual maturity and metabolic control. METHOD: This is a cross-sectional study conducted with 94 adolescents between 10 and 20 years of age, with early diagnosis and continuous treatment. Bioimpedance, weight measurements, height and BMI calculation were performed. Questionnaires were applied to quantify protein ingestion and establish the level of physical activity. Sexual maturity was assessed using the Tanner criteria. The annual mean of serum phenylalanine was used as a control parameter of the disease. A multivariate linear regression analysis was performed. RESULTS: Overweight, obesity, the female sex and the percentage of protein consumption explain 94.1% of the % BF of the patients (p < .05). The overweight prevalence was 19.1%. It was verified that 96.7% of the sample were sedentary. Only 50 (53.2%) of the adolescents had good treatment compliance, and no relationship was found between this variable and the % BF (p = .706). CONCLUSIONS: Being female and presenting high BMI values are important factors associated with % BF in phenylketonuric adolescents. Disease control and protein consumption do not seem to influence the body composition.
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spelling pubmed-72253912020-05-18 Body fat percentage in adolescents with phenylketonuria and associated factors Camatta, Giovanna Caliman Kanufre, Viviane de Cássia Alves, Michelle Rosa Andrade Soares, Rosângelis Del Lama Norton, Rocksane de Carvalho de Aguiar, Marcos José Burle Starling, Ana Lúcia Pimenta Mol Genet Metab Rep Research Paper OBJECTIVE: To evaluate the percentage of body fat (% BF) in adolescents with PKU and to relate it to protein consumption, physical activity level, body mass index (BMI), sexual maturity and metabolic control. METHOD: This is a cross-sectional study conducted with 94 adolescents between 10 and 20 years of age, with early diagnosis and continuous treatment. Bioimpedance, weight measurements, height and BMI calculation were performed. Questionnaires were applied to quantify protein ingestion and establish the level of physical activity. Sexual maturity was assessed using the Tanner criteria. The annual mean of serum phenylalanine was used as a control parameter of the disease. A multivariate linear regression analysis was performed. RESULTS: Overweight, obesity, the female sex and the percentage of protein consumption explain 94.1% of the % BF of the patients (p < .05). The overweight prevalence was 19.1%. It was verified that 96.7% of the sample were sedentary. Only 50 (53.2%) of the adolescents had good treatment compliance, and no relationship was found between this variable and the % BF (p = .706). CONCLUSIONS: Being female and presenting high BMI values are important factors associated with % BF in phenylketonuric adolescents. Disease control and protein consumption do not seem to influence the body composition. Elsevier 2020-05-12 /pmc/articles/PMC7225391/ /pubmed/32426233 http://dx.doi.org/10.1016/j.ymgmr.2020.100595 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Research Paper
Camatta, Giovanna Caliman
Kanufre, Viviane de Cássia
Alves, Michelle Rosa Andrade
Soares, Rosângelis Del Lama
Norton, Rocksane de Carvalho
de Aguiar, Marcos José Burle
Starling, Ana Lúcia Pimenta
Body fat percentage in adolescents with phenylketonuria and associated factors
title Body fat percentage in adolescents with phenylketonuria and associated factors
title_full Body fat percentage in adolescents with phenylketonuria and associated factors
title_fullStr Body fat percentage in adolescents with phenylketonuria and associated factors
title_full_unstemmed Body fat percentage in adolescents with phenylketonuria and associated factors
title_short Body fat percentage in adolescents with phenylketonuria and associated factors
title_sort body fat percentage in adolescents with phenylketonuria and associated factors
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225391/
https://www.ncbi.nlm.nih.gov/pubmed/32426233
http://dx.doi.org/10.1016/j.ymgmr.2020.100595
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