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MRPA-independent mechanisms of antimony resistance in Leishmania infantum

Control of both human and canine leishmaniasis is based on a very short list of chemotherapeutic agents, headed by antimonial derivatives (Sb). The utility of these molecules is severely threatened by high rates of drug resistance. The ABC transporter MRPA is one of the few key Sb resistance protein...

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Detalles Bibliográficos
Autores principales: Douanne, Noélie, Wagner, Victoria, Roy, Gaetan, Leprohon, Philippe, Ouellette, Marc, Fernandez-Prada, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225602/
https://www.ncbi.nlm.nih.gov/pubmed/32413766
http://dx.doi.org/10.1016/j.ijpddr.2020.03.003

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