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Myopic regression and recurrent Salzmann nodule degeneration after laser in situ keratomileusis in Ehlers Danlos Syndrome
PURPOSE: We describe the first case of Ehlers Danlos Syndrome (EDS) reported in the English language ophthalmic literature to have undergone Laser In Situ Keratomileusis (LASIK) surgery. OBSERVATIONS: We review our patient's specific postoperative complications of myopic regression, Salzmann no...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225616/ https://www.ncbi.nlm.nih.gov/pubmed/32426553 http://dx.doi.org/10.1016/j.ajoc.2020.100729 |
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author | Hopping, Grant C. Somani, Anisha N. Vaidyanathan, Uma Liu, Harry Barnes, James R. Ronquillo, Yasmyne C. Hoopes, Phillip C. Moshirfar, Majid |
author_facet | Hopping, Grant C. Somani, Anisha N. Vaidyanathan, Uma Liu, Harry Barnes, James R. Ronquillo, Yasmyne C. Hoopes, Phillip C. Moshirfar, Majid |
author_sort | Hopping, Grant C. |
collection | PubMed |
description | PURPOSE: We describe the first case of Ehlers Danlos Syndrome (EDS) reported in the English language ophthalmic literature to have undergone Laser In Situ Keratomileusis (LASIK) surgery. OBSERVATIONS: We review our patient's specific postoperative complications of myopic regression, Salzmann nodular degeneration, and dry eye syndrome, as well as the risks and consequences of performing LASIK on patients with this collagen disorder. CONCLUSIONS AND IMPORTANCE: Refractive errors may prompt EDS patients to seek laser vision correction, placing them at increased risk for complications such as myopic regression, keratectasia, and dry eye syndrome. Aberrant wound healing and collagen dysfunction may have influenced our patient's myopic regression and Salzmann nodule degeneration post-LASIK. Currently, EDS is considered a relative contraindication in LASIK due to a presumed higher risk of postoperative keratectasia; however, we believe it is possible that not all forms of EDS need to be an absolute contraindication to LASIK. More research is warranted to determine preoperative risk stratification for laser vision surgery in each subtype of EDS. |
format | Online Article Text |
id | pubmed-7225616 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-72256162020-05-18 Myopic regression and recurrent Salzmann nodule degeneration after laser in situ keratomileusis in Ehlers Danlos Syndrome Hopping, Grant C. Somani, Anisha N. Vaidyanathan, Uma Liu, Harry Barnes, James R. Ronquillo, Yasmyne C. Hoopes, Phillip C. Moshirfar, Majid Am J Ophthalmol Case Rep Case Report PURPOSE: We describe the first case of Ehlers Danlos Syndrome (EDS) reported in the English language ophthalmic literature to have undergone Laser In Situ Keratomileusis (LASIK) surgery. OBSERVATIONS: We review our patient's specific postoperative complications of myopic regression, Salzmann nodular degeneration, and dry eye syndrome, as well as the risks and consequences of performing LASIK on patients with this collagen disorder. CONCLUSIONS AND IMPORTANCE: Refractive errors may prompt EDS patients to seek laser vision correction, placing them at increased risk for complications such as myopic regression, keratectasia, and dry eye syndrome. Aberrant wound healing and collagen dysfunction may have influenced our patient's myopic regression and Salzmann nodule degeneration post-LASIK. Currently, EDS is considered a relative contraindication in LASIK due to a presumed higher risk of postoperative keratectasia; however, we believe it is possible that not all forms of EDS need to be an absolute contraindication to LASIK. More research is warranted to determine preoperative risk stratification for laser vision surgery in each subtype of EDS. Elsevier 2020-05-04 /pmc/articles/PMC7225616/ /pubmed/32426553 http://dx.doi.org/10.1016/j.ajoc.2020.100729 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Hopping, Grant C. Somani, Anisha N. Vaidyanathan, Uma Liu, Harry Barnes, James R. Ronquillo, Yasmyne C. Hoopes, Phillip C. Moshirfar, Majid Myopic regression and recurrent Salzmann nodule degeneration after laser in situ keratomileusis in Ehlers Danlos Syndrome |
title | Myopic regression and recurrent Salzmann nodule degeneration after laser in situ keratomileusis in Ehlers Danlos Syndrome |
title_full | Myopic regression and recurrent Salzmann nodule degeneration after laser in situ keratomileusis in Ehlers Danlos Syndrome |
title_fullStr | Myopic regression and recurrent Salzmann nodule degeneration after laser in situ keratomileusis in Ehlers Danlos Syndrome |
title_full_unstemmed | Myopic regression and recurrent Salzmann nodule degeneration after laser in situ keratomileusis in Ehlers Danlos Syndrome |
title_short | Myopic regression and recurrent Salzmann nodule degeneration after laser in situ keratomileusis in Ehlers Danlos Syndrome |
title_sort | myopic regression and recurrent salzmann nodule degeneration after laser in situ keratomileusis in ehlers danlos syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225616/ https://www.ncbi.nlm.nih.gov/pubmed/32426553 http://dx.doi.org/10.1016/j.ajoc.2020.100729 |
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