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Increased levels of 5′,8-Cyclopurine DNA lesions in inflammatory bowel diseases

Chronic inflammation is estimated to be a causative factor in a variety of diseases. Under inflammatory conditions reactive oxygen species (ROS) and nitrogen species (RNS) are released leading to DNA damage accumulation and genomic instability. Purine 5′,8-cyclo-2′-deoxynucleosides (cPu) are oxidati...

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Detalles Bibliográficos
Autores principales:	Masi, Annalisa, Fortini, Paola, Krokidis, Marios G., Romeo, Erminia Francesca, Bascietto, Cinzia, De Angelis, Paola, Guglielmi, Valeria, Chatgilialoglu, Chryssostomos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225727/ https://www.ncbi.nlm.nih.gov/pubmed/32413746 http://dx.doi.org/10.1016/j.redox.2020.101562

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