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High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation

This work investigates the relationship between high-glucose (HG) culture, CpG methylation of genes involved in cell signaling pathways, and the regulation of carbohydrate and lipid metabolism in hepatocytes. The results indicate that HG leads to an increase in nuclear 25-hydroxycholesterol (25HC),...

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Detalles Bibliográficos
Autores principales:	Wang, Yaping, Chen, Lanming, Pandak, William M., Heuman, Douglas, Hylemon, Phillip B., Ren, Shunlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225732/ https://www.ncbi.nlm.nih.gov/pubmed/32408171 http://dx.doi.org/10.1016/j.isci.2020.101102

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