Cargando…

Induced pluripotent stem cell-derived enteric neural crest cells repopulate human aganglionic tissue-engineered intestine to form key components of the enteric nervous system

Models for enteric neuropathies, in which intestinal nerves are absent or injured, are required to evaluate possible cell therapies. However, existing options, including transgenic mice, are variable and fragile. Here immunocompromised mice were implanted with human pluripotent stem cell–derived tis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, David F, Zuber, Samuel M, Gilliam, Elizabeth A, Nucho, Laura-Marie A, Levin, Gabriel, Wang, Fengnan, Squillaro, Anthony I, Huang, Sha, Spence, Jason R, Grikscheit, Tracy C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225796/ https://www.ncbi.nlm.nih.gov/pubmed/32435442 http://dx.doi.org/10.1177/2041731420905701

Ejemplares similares

Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine
por: Schlieve, Christopher R., et al.
Publicado: (2017)

Isolation of Enteric Nervous System Progenitor Cells from the Aganglionic Gut of Patients with Hirschsprung’s Disease
por: Wilkinson, David J., et al.
Publicado: (2015)

Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells
por: Li, W, et al.
Publicado: (2018)

Cancer Cells Enter an Adaptive Persistence to Survive Radiotherapy and Repopulate Tumor
por: Zhao, Yucui, et al.
Publicado: (2023)

Postnatal human enteric neuronal progenitors can migrate, differentiate, and proliferate in embryonic and postnatal aganglionic gut environments
por: Cheng, Lily S., et al.
Publicado: (2017)

Why are enteric ganglia so small? Role of differential adhesion of enteric neurons and enteric neural crest cells.
por: Rollo, Benjamin N., et al.
Publicado: (2015)

New insights empowered by single-cell sequencing: From neural crest to enteric nervous system
por: Li, Zhixin, et al.
Publicado: (2022)

Ablation of Ezh2 in neural crest cells leads to aberrant enteric nervous system development in mice
por: Kim, Hana, et al.
Publicado: (2018)

Vascularisation is not necessary for gut colonisation by enteric neural crest cells()
por: Delalande, Jean-Marie, et al.
Publicado: (2014)

Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development
por: Uribe, Rosa A., et al.
Publicado: (2015)

Single-cell profiling coupled with lineage analysis reveals vagal and sacral neural crest contributions to the developing enteric nervous system
por: Jacobs-Li, Jessica, et al.
Publicado: (2023)

How Tissue Mechanical Properties Affect Enteric Neural Crest Cell Migration
por: Chevalier, N.R., et al.
Publicado: (2016)

In vivo transplantation of fetal human gut‐derived enteric neural crest cells
por: Cooper, J. E., et al.
Publicado: (2016)

Alteration of the Retinoid Acid-CBP Signaling Pathway in Neural Crest Induction Contributes to Enteric Nervous System Disorder
por: Li, Cheng, et al.
Publicado: (2018)

Mechanosensitivity in the enteric nervous system
por: Mazzuoli-Weber, Gemma, et al.
Publicado: (2015)

Mycotoxins and the Enteric Nervous System
por: Gonkowski, Sławomir, et al.
Publicado: (2020)

The Aging Enteric Nervous System
por: Nguyen, Tinh Thi, et al.
Publicado: (2023)

Roles of Enteric Neural Stem Cell Niche and Enteric Nervous System Development in Hirschsprung Disease
por: Ji, Yue, et al.
Publicado: (2021)

R-Spondin 1 (RSPO1) Increases Mouse Intestinal Organoid Unit Size and Survival in vitro and Improves Tissue-Engineered Small Intestine Formation in vivo
por: Levin, Gabriel, et al.
Publicado: (2020)

Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut
por: Fu, Ming, et al.
Publicado: (2004)

Enteric Neurospheres Are Not Specific to Neural Crest Cultures: Implications for Neural Stem Cell Therapies
por: Binder, Ellen, et al.
Publicado: (2015)

Corrigendum: How Tissue Mechanical Properties Affect Enteric Neural Crest Cell Migration
por: Chevalier, N. R., et al.
Publicado: (2016)

Colonizing while migrating: how do individual enteric neural crest cells behave?
por: Young, Heather M, et al.
Publicado: (2014)

Ret deficiency decreases neural crest progenitor proliferation and restricts fate potential during enteric nervous system development
por: Vincent, Elizabeth, et al.
Publicado: (2023)

Geminin prevents DNA damage in vagal neural crest cells to ensure normal enteric neurogenesis
por: Konstantinidou, Chrysoula, et al.
Publicado: (2016)

Applications of Single-Cell Sequencing Technology to the Enteric Nervous System
por: Guyer, Richard A., et al.
Publicado: (2022)

The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems
por: Carabotti, Marilia, et al.
Publicado: (2015)

Exposure to GDNF Enhances the Ability of Enteric Neural Progenitors to Generate an Enteric Nervous System
por: McKeown, Sonja J., et al.
Publicado: (2017)

The Enteric Nervous System and Its Emerging Role as a Therapeutic Target
por: Fleming, Mark A., et al.
Publicado: (2020)

Schwann Cells in the Aganglionic Colon of Hirschsprung Disease Can Generate Neurons for Regenerative Therapy
por: Pan, Weikang, et al.
Publicado: (2022)

Intestinal fibrosis in aganglionic segment of Hirschsprung's disease revealed by single‐cell RNA sequencing
por: He, Shiwei, et al.
Publicado: (2023)

Dietary Glutamate: Interactions With the Enteric Nervous System
por: Wang, Guo-Du, et al.
Publicado: (2014)

The enteric nervous system in gastrointestinal disease etiology
por: Holland, Amy Marie, et al.
Publicado: (2021)

Neuroprotective Effects of VEGF in the Enteric Nervous System
por: Hecking, Ines, et al.
Publicado: (2022)

Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks
por: De Vadder, Filipe, et al.
Publicado: (2018)

Genome-wide analysis of DNA methylation in Hirschsprung enteric precursor cells: unraveling the epigenetic landscape of enteric nervous system development
por: Villalba-Benito, Leticia, et al.
Publicado: (2021)

Ancient evolutionary origin of vertebrate enteric neurons from trunk-derived neural crest
por: Green, Stephen A., et al.
Publicado: (2017)

In Vivo Transplantation of Enteric Neural Crest Cells into Mouse Gut; Engraftment, Functional Integration and Long-Term Safety
por: Cooper, Julie E., et al.
Publicado: (2016)

Control of the collective migration of enteric neural crest cells by the Complement anaphylatoxin C3a and N-cadherin
por: Broders-Bondon, Florence, et al.
Publicado: (2016)

Phenotypic and functional comparison of rat enteric neural crest-derived cells during fetal and early-postnatal stages
por: Tian, Dong-Hao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4oj9no8ik8l1jpvfd0edplv6ol