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p53 and FBXW7: Sometimes Two Guardians Are Worse than One
Too much of a good thing can become a bad thing. An example is FBXW7, a well-known tumor suppressor that may also contribute to tumorigenesis. Here, we reflect on the results of three laboratories describing the role of FBXW7 in the degradation of p53 and the possible implications of this finding in...
Autores principales: | Galindo-Moreno, María, Giráldez, Servando, Limón-Mortés, M. Cristina, Belmonte-Fernández, Alejandro, Sáez, Carmen, Japón, Miguel Á., Tortolero, Maria, Romero, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225930/ https://www.ncbi.nlm.nih.gov/pubmed/32316282 http://dx.doi.org/10.3390/cancers12040985 |
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