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Activation of α7 Nicotinic Acetylcholine Receptor Upregulates HLA-DR and Macrophage Receptors: Potential Role in Adaptive Immunity and in Preventing Immunosuppression

Immune response during sepsis is characterized by hyper-inflammation followed by immunosuppression. The crucial role of macrophages is well-known for both septic stages, since they are involved in immune homeostasis and inflammation, their dysfunction being implicated in immunosuppression. The choli...

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Detalles Bibliográficos
Autores principales: Siniavin, Andrei E., Streltsova, Maria A., Kudryavtsev, Denis S., Shelukhina, Irina V., Utkin, Yuri N., Tsetlin, Victor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225944/
https://www.ncbi.nlm.nih.gov/pubmed/32230846
http://dx.doi.org/10.3390/biom10040507