Cargando…
Novel Apoptotic Mediators Identified by Conservation of Vertebrate Caspase Targets
Caspases are proteases conserved throughout Metazoans and responsible for initiating and executing the apoptotic program. Currently, there are over 1800 known apoptotic caspase substrates, many of them known regulators of cell proliferation and death, which makes them attractive therapeutic targets....
Autores principales: | Gubina, Nina, Leboeuf, Dominique, Piatkov, Konstantin, Pyatkov, Maxim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225963/ https://www.ncbi.nlm.nih.gov/pubmed/32326640 http://dx.doi.org/10.3390/biom10040612 |
Ejemplares similares
-
The Arg/N-Degron Pathway—A Potential Running Back in Fine-Tuning the Inflammatory Response?
por: Leboeuf, Dominique, et al.
Publicado: (2020) -
Are membranes non-apoptotic compartments for apoptotic caspases?
por: Bergmann, Andreas
Publicado: (2018) -
Preclinical Studies Identify Non-Apoptotic Low-Level Caspase-3 as Therapeutic Target in Pemphigus Vulgaris
por: Luyet, Camille, et al.
Publicado: (2015) -
Evidence for a Novel, Caspase-8-Independent, Fas Death
Domain-Mediated Apoptotic Pathway
por: Feng, Hanping, et al.
Publicado: (2004) -
Non-Apoptotic Role of Apoptotic Caspases in the Drosophila Nervous System
por: Colon-Plaza, Sarah, et al.
Publicado: (2022)