Uric Acid Has Direct Proinflammatory Effects on Human Macrophages by Increasing Proinflammatory Mediators and Bacterial Phagocytosis Probably via URAT1

The relationship of uric acid with macrophages has not been fully elucidated. We investigated the effect of uric acid on the proinflammatory ability of human macrophages and then examined the possible molecular mechanism involved. Primary human monocytes were differentiated into macrophages for subs...

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Detalles Bibliográficos
Autores principales: Martínez-Reyes, Camilo P., Manjarrez-Reyna, Aarón N., Méndez-García, Lucia A., Aguayo-Guerrero, José A., Aguirre-Sierra, Beatriz, Villalobos-Molina, Rafael, López-Vidal, Yolanda, Bobadilla, Karen, Escobedo, Galileo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225983/
https://www.ncbi.nlm.nih.gov/pubmed/32283759
http://dx.doi.org/10.3390/biom10040576

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