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Exogenous NAD(+) Stimulates MUC2 Expression in LS 174T Goblet Cells via the PLC-Delta/PTGES/PKC-Delta/ERK/CREB Signaling Pathway

Background: MUC2, a major component of the mucus layer in the intestine, is associated with antimicrobial activity and gut immune system function. Currently, mucin is mainly known for its critical function in defense against toxic molecules and pathogens. In this study, we investigated the stimulato...

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Detalles Bibliográficos
Autores principales: Ma, Seongho, Yeom, Jiah, Lim, Young-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226023/
https://www.ncbi.nlm.nih.gov/pubmed/32283838
http://dx.doi.org/10.3390/biom10040580