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VIRMA-Dependent N6-Methyladenosine Modifications Regulate the Expression of Long Non-Coding RNAs CCAT1 and CCAT2 in Prostate Cancer

RNA methylation at position N6 in adenosine (m(6)A) and its associated methyltransferase complex (MTC) are involved in tumorigenesis. We aimed to explore m(6)A biological function for long non-coding RNAs (lncRNAs) in prostate cancer (PCa) and its clinical significance. m(6)A and MTC levels in PCa c...

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Detalles Bibliográficos
Autores principales: Barros-Silva, Daniela, Lobo, João, Guimarães-Teixeira, Catarina, Carneiro, Isa, Oliveira, Jorge, Martens-Uzunova, Elena S., Henrique, Rui, Jerónimo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226055/
https://www.ncbi.nlm.nih.gov/pubmed/32218194
http://dx.doi.org/10.3390/cancers12040771