Cargando…

Cisplatin Relocalizes RNA Binding Protein HuR and Enhances the Oncolytic Activity of E4orf6 Deleted Adenovirus

The combination of adenoviruses and chemotherapy agents is a novel approach for human cancer therapeutics. A meticulous analysis between adenovirus and chemotherapeutic agents can help to design an effective anticancer therapy. Human antigen R (HuR) is an RNA binding protein that binds to the AU-ric...

Descripción completa

Detalles Bibliográficos
Autores principales:	Habiba, Umma, Hossain, Elora, Yanagawa-Matsuda, Aya, Chowdhury, Abu Faem Mohammad Almas, Tsuda, Masumi, Zaman, Asad-uz-, Tanaka, Shinya, Higashino, Fumihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226092/ https://www.ncbi.nlm.nih.gov/pubmed/32230919 http://dx.doi.org/10.3390/cancers12040809

Ejemplares similares

Advantages of Using Paclitaxel in Combination with Oncolytic Adenovirus Utilizing RNA Destabilization Mechanism
por: Hossain, Elora, et al.
Publicado: (2020)

HuR and podoplanin expression is associated with a high risk of malignant transformation in patients with oral preneoplastic lesions
por: Habiba, Umma, et al.
Publicado: (2016)

Cytoplasmic expression of HuR may be a valuable diagnostic tool for determining the potential for malignant transformation of oral verrucous borderline lesions
por: HABIBA, UMMA, et al.
Publicado: (2014)

Conditionally Replicative Adenovirus Controlled by the Stabilization System of AU-Rich Elements Containing mRNA
por: Mikawa, Yohei, et al.
Publicado: (2020)

Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence
por: Yi, Jie, et al.
Publicado: (2010)

MCD Diet Modulates HuR and Oxidative Stress-Related HuR Targets in Rats
por: Ferrigno, Andrea, et al.
Publicado: (2023)

Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
por: Yang, Feng, et al.
Publicado: (2019)

Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs
por: Yoon, Je-Hyun, et al.
Publicado: (2014)

The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro
por: Kaur, Kawaljit, et al.
Publicado: (2017)

Correction: Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
por: Yang, Feng, et al.
Publicado: (2023)

HuB and HuD repress telomerase activity by dissociating HuR from TERC
por: Cheng, Xiaolei, et al.
Publicado: (2021)

Regulation of HuR by DNA Damage Response Kinases
por: Kim, Hyeon Ho, et al.
Publicado: (2010)

Regulation of HuR structure and function by dihydrotanshinone-I
por: Lal, Preet, et al.
Publicado: (2017)

Hu Antigen R (HuR) Protein Structure, Function and Regulation in Hepatobiliary Tumors
por: Lachiondo-Ortega, Sofia, et al.
Publicado: (2022)

HuR is exported to the cytoplasm in oral cancer cells in a different manner from that of normal cells
por: Hasegawa, H, et al.
Publicado: (2009)

Regulation of AT1R expression through HuR by insulin
por: Paukku, Kirsi, et al.
Publicado: (2012)

MiR-200c and HuR in ovarian cancer
por: Prislei, Silvia, et al.
Publicado: (2013)

HuR regulates telomerase activity through TERC methylation
por: Tang, Hao, et al.
Publicado: (2018)

Glycyrrhetinic Acid Maintains Intestinal Homeostasis via HuR
por: Chen, Gang, et al.
Publicado: (2019)

The RNA-Binding Protein HuR in Digestive System Tumors
por: Song, Xiaoqing, et al.
Publicado: (2020)

HuR modulation counteracts lipopolysaccharide response in murine macrophages
por: Bonomo, Isabelle, et al.
Publicado: (2023)

HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
por: Kurosu, T, et al.
Publicado: (2011)

HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth
por: Liebig, Janika K., et al.
Publicado: (2020)

ALDH1 and podoplanin expression patterns predict the risk of malignant transformation in oral leukoplakia
por: Habiba, Umma, et al.
Publicado: (2017)

Different modes of interaction by TIAR and HuR with target RNA and DNA
por: Kim, Henry S., et al.
Publicado: (2011)

The Role of HuR in the Post-Transcriptional Regulation of Interleukin-3 in T Cells
por: González-Feliciano, José A., et al.
Publicado: (2014)

Clinical Significance and Biological Role of HuR in Head and Neck Carcinomas
por: Levidou, Georgia, et al.
Publicado: (2018)

The RNA-binding protein HuR is a negative regulator in adipogenesis
por: Siang, Diana Teh Chee, et al.
Publicado: (2020)

HuR Protein in Hepatocellular Carcinoma: Implications in Development, Prognosis and Treatment
por: Papatheofani, Vasiliki, et al.
Publicado: (2021)

Eltrombopag Inhibits Metastasis in Breast Carcinoma by Targeting HuR Protein
por: Chen, Yao, et al.
Publicado: (2023)

Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation
por: Mansfield, Kyle D., et al.
Publicado: (2012)

Correction: The Role of HuR in the Post-Transcriptional Regulation of Interleukin-3 in T Cells
Publicado: (2014)

7SL RNA represses p53 translation by competing with HuR
por: Abdelmohsen, Kotb, et al.
Publicado: (2014)

Loss of CARM1 is linked to reduced HuR function in replicative senescence
por: Pang, Lijun, et al.
Publicado: (2013)

Downregulation of β-Adrenoceptors in Isoproterenol-Induced Cardiac Remodeling through HuR
por: Yin, Qian, et al.
Publicado: (2016)

Growth Factor Dependent Regulation of Centrosome Function and Genomic Instability by HuR
por: Filippova, Natalia, et al.
Publicado: (2015)

Author Correction: HuR regulates telomerase activity through TERC methylation
por: Tang, Hao, et al.
Publicado: (2018)

Downregulation of HuR Inhibits the Progression of Esophageal Cancer through Interleukin-18
por: Xu, Xiaohui, et al.
Publicado: (2018)

Post-transcriptional regulation of Pabpn1 by the RNA binding protein HuR
por: Phillips, Brittany L, et al.
Publicado: (2018)

Adipose HuR protects against diet-induced obesity and insulin resistance
por: Li, Jingyuan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_41f6pb17hgv5q43haepuffbfss