Cargando…

Erbb4 Is Required for Cerebellar Development and Malignant Phenotype of Medulloblastoma

Medulloblastoma is the most common and malignant pediatric brain tumor in childhood. It originates from dysregulation of cerebellar development, due to an excessive proliferation of cerebellar granule neuron precursor cells (CGNPs). The underlying molecular mechanisms, except for the role of SHH and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aldaregia, Juncal, Errarte, Peio, Olazagoitia-Garmendia, Ane, Gimeno, Marian, Uriz, Jose Javier, Gershon, Timothy R., Garcia, Idoia, Matheu, Ander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226104/ https://www.ncbi.nlm.nih.gov/pubmed/32316671 http://dx.doi.org/10.3390/cancers12040997

Ejemplares similares

Targeting mTOR as a Therapeutic Approach in Medulloblastoma
por: Aldaregia, Juncal, et al.
Publicado: (2018)

SOX9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycin
por: Carrasco-Garcia, Estefania, et al.
Publicado: (2016)

Bax-deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation
por: Garcia, Idoia, et al.
Publicado: (2012)

Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma
por: Gershon, Timothy R, et al.
Publicado: (2013)

Oncogenic activity of SOX1 in glioblastoma
por: Garcia, Idoia, et al.
Publicado: (2017)

Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation
por: Zindy, Frederique, et al.
Publicado: (2015)

Adult hemispheric cerebellar medulloblastoma
por: de Oliveira, Felipe, et al.
Publicado: (2018)

Extra-Axial Medulloblastoma in the Cerebellar Hemisphere
por: Chung, Eui Jin, et al.
Publicado: (2014)

Cerebellar Medulloblastoma in Middle-to-Late Adulthood
por: Aljoghaiman, Majid, et al.
Publicado: (2018)

The role of cancer-associated fibroblasts in renal cell carcinoma. An example of tumor modulation through tumor/non-tumor cell interactions
por: Errarte, Peio, et al.
Publicado: (2019)

Functional evolutionary convergence of long noncoding RNAs involved in embryonic development
por: Olazagoitia-Garmendia, Ane, et al.
Publicado: (2023)

PRC2 disruption in cerebellar progenitors produces cerebellar hypoplasia and aberrant myoid differentiation without blocking medulloblastoma growth
por: Cleveland, Abigail H., et al.
Publicado: (2023)

Modeling medulloblastoma in vivo and with human cerebellar organoids
por: Ballabio, Claudio, et al.
Publicado: (2020)

Sonic Hedgehog-Induced Histone Deacetylase Activation Is Required for Cerebellar Granule Precursor Hyperplasia in Medulloblastoma
por: Lee, Seung Joon, et al.
Publicado: (2013)

Shaping Up Zn-Doped Magnetite Nanoparticles from Mono- and Bimetallic Oleates: The Impact of Zn Content, Fe Vacancies, and Morphology on Magnetic Hyperthermia Performance
por: Castellanos-Rubio, Idoia, et al.
Publicado: (2021)

A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation
por: Castellanos-Rubio, Ainara, et al.
Publicado: (2019)

Integrated mRNA and miRNA Transcriptomic Analyses Reveals Divergent Mechanisms of Sunitinib Resistance in Clear Cell Renal Cell Carcinoma (ccRCC)
por: Armesto, María, et al.
Publicado: (2021)

The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma
por: Vriend, Jerry, et al.
Publicado: (2015)

Prognostic significance of the c-erbB-2 oncogene product in childhood medulloblastoma.
por: Gilbertson, R. J., et al.
Publicado: (1995)

The Role of lncRNAs in Gene Expression Regulation through mRNA Stabilization
por: Sebastian-delaCruz, Maialen, et al.
Publicado: (2021)

Fatal cerebellar hemorrhage as an initial presentation of medulloblastoma in a child
por: Menekse, Guner, et al.
Publicado: (2015)

Editorial: Cerebellar development and medulloblastoma: new players and therapeutic options
por: Ceccarelli, Manuela
Publicado: (2023)

MBRS-08. SONIC HEDGEHOG SIGNALING PRIMES CEREBELLAR GRANULE NEURON PROGENITORS, THE CELL OF ORIGIN FOR MEDULLOBLASTOMA, FOR APOPTOSIS BY INDUCING PRO APOPTOTIC BIM
por: Cleveland, Abigail, et al.
Publicado: (2020)

Simultaneous occurrence of cerebellar medulloblastoma and pituitary adenoma: A case report
por: Samaras, Vassilis, et al.
Publicado: (2008)

Implication of m6A mRNA Methylation in Susceptibility to Inflammatory Bowel Disease
por: Sebastian-delaCruz, Maialen, et al.
Publicado: (2020)

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog - dependent cerebellar granule neuron progenitor cells and medulloblastoma cells
por: Dey, Abhinav, et al.
Publicado: (2016)

Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines
por: Zomerman, Walderik W., et al.
Publicado: (2015)

Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor
por: Vaquero, Encarna, et al.
Publicado: (2008)

Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development
por: Zindy, Frederique, et al.
Publicado: (2014)

Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells
por: Kawauchi, D, et al.
Publicado: (2017)

Clinical and magnetic resonance imaging findings of a cerebellar medulloblastoma in a heifer
por: Francesio, Andrea, et al.
Publicado: (2018)

The Role of Apparent Diffusion Coefficient in the Differentiation between Cerebellar Medulloblastoma and Brainstem Glioma
por: Minh Thong, Pham, et al.
Publicado: (2020)

Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review
por: Dong, Changhui, et al.
Publicado: (2021)

Highly Reproducible Hyperthermia Response in Water, Agar, and Cellular Environment by Discretely PEGylated Magnetite Nanoparticles
por: Castellanos-Rubio, Idoia, et al.
Publicado: (2020)

MAGI2 Gene Region and Celiac Disease
por: Jauregi-Miguel, Amaia, et al.
Publicado: (2019)

Trimethylation of H3K27 during human cerebellar development in relation to medulloblastoma
por: Mir, Shahryar E., et al.
Publicado: (2017)

Delayed diffuse cerebellar swelling after resection of medulloblastoma: case report and review of literature
por: Raghu, Ashley L. B., et al.
Publicado: (2017)

MDB-05. HUMAN FETAL CEREBELLAR CELL ATLAS INFORMS MEDULLOBLASTOMA ORIGIN AND ONCOGENESIS
por: Luo, Zaili, et al.
Publicado: (2023)

Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma
por: Vaillant, Catherine, et al.
Publicado: (2015)

ERBB3 is required for metastasis formation of melanoma cells
por: Tiwary, S, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9a6ia44au63fchkmgto5tnk69i