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High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases

There is limited understanding of the specific role of high-density lipoprotein cholesterol (HDL-C) in the development of various age-related ocular diseases, despite it being a common measurable biomarker in lipid profiles. This literature review summarizes current knowledge of the role of HDL-C, i...

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Detalles Bibliográficos
Autores principales: Betzler, Bjorn Kaijun, Rim, Tyler Hyungtaek, Sabanayagam, Charumathi, Cheung, Chui Ming Gemmy, Cheng, Ching-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226134/
https://www.ncbi.nlm.nih.gov/pubmed/32331355
http://dx.doi.org/10.3390/biom10040645
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author Betzler, Bjorn Kaijun
Rim, Tyler Hyungtaek
Sabanayagam, Charumathi
Cheung, Chui Ming Gemmy
Cheng, Ching-Yu
author_facet Betzler, Bjorn Kaijun
Rim, Tyler Hyungtaek
Sabanayagam, Charumathi
Cheung, Chui Ming Gemmy
Cheng, Ching-Yu
author_sort Betzler, Bjorn Kaijun
collection PubMed
description There is limited understanding of the specific role of high-density lipoprotein cholesterol (HDL-C) in the development of various age-related ocular diseases, despite it being a common measurable biomarker in lipid profiles. This literature review summarizes current knowledge of the role of HDL-C, if any, in pathogenesis and progression of four age-related ocular diseases, namely age-related macular degeneration (AMD), age-related cataract, glaucoma, and diabetic retinopathy (DR), and will primarily discuss epidemiological and genetic evidence.
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spelling pubmed-72261342020-05-18 High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases Betzler, Bjorn Kaijun Rim, Tyler Hyungtaek Sabanayagam, Charumathi Cheung, Chui Ming Gemmy Cheng, Ching-Yu Biomolecules Review There is limited understanding of the specific role of high-density lipoprotein cholesterol (HDL-C) in the development of various age-related ocular diseases, despite it being a common measurable biomarker in lipid profiles. This literature review summarizes current knowledge of the role of HDL-C, if any, in pathogenesis and progression of four age-related ocular diseases, namely age-related macular degeneration (AMD), age-related cataract, glaucoma, and diabetic retinopathy (DR), and will primarily discuss epidemiological and genetic evidence. MDPI 2020-04-22 /pmc/articles/PMC7226134/ /pubmed/32331355 http://dx.doi.org/10.3390/biom10040645 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Betzler, Bjorn Kaijun
Rim, Tyler Hyungtaek
Sabanayagam, Charumathi
Cheung, Chui Ming Gemmy
Cheng, Ching-Yu
High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases
title High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases
title_full High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases
title_fullStr High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases
title_full_unstemmed High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases
title_short High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases
title_sort high-density lipoprotein cholesterol in age-related ocular diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226134/
https://www.ncbi.nlm.nih.gov/pubmed/32331355
http://dx.doi.org/10.3390/biom10040645
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