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The Road Not Taken with Pyrrole-Imidazole Polyamides: Off-Target Effects and Genomic Binding
The high sequence specificity of minor groove-binding N-methylpyrrole-N-methylimidazole polyamides have made significant advances in cancer and disease biology, yet there have been few comprehensive reports on their off-target effects, most likely as a consequence of the lack of available tools in e...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226143/ https://www.ncbi.nlm.nih.gov/pubmed/32260120 http://dx.doi.org/10.3390/biom10040544 |