Cargando…

A Matter of Choice: Inhibition of c-Rel Shifts Neuronal to Oligodendroglial Fate in Human Stem Cells

The molecular mechanisms underlying fate decisions of human neural stem cells (hNSCs) between neurogenesis and gliogenesis are critical during neuronal development and neurodegenerative diseases. Despite its crucial role in the murine nervous system, the potential role of the transcription factor NF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ruiz-Perera, Lucia Mercedes, Greiner, Johannes Friedrich Wilhelm, Kaltschmidt, Christian, Kaltschmidt, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226153/ https://www.ncbi.nlm.nih.gov/pubmed/32331232 http://dx.doi.org/10.3390/cells9041037

Ejemplares similares

Between Fate Choice and Self-Renewal—Heterogeneity of Adult Neural Crest-Derived Stem Cells
por: Höving, Anna L., et al.
Publicado: (2021)

CRISPR/Cas9-mediated knockout of c-REL in HeLa cells results in profound defects of the cell cycle
por: Slotta, Carsten, et al.
Publicado: (2017)

NF-κB p65 directs sex-specific neuroprotection in human neurons
por: Ruiz-Perera, Lucia M., et al.
Publicado: (2018)

EPO regulates neuronal differentiation of adult human neural-crest derived stem cells in a sex-specific manner
por: Niemann, Tarek, et al.
Publicado: (2023)

The Transcription Factor NF-κB in Stem Cells and Development
por: Kaltschmidt, Christian, et al.
Publicado: (2021)

Neuroprotection Mediated by Human Blood Plasma in Mouse Hippocampal Slice Cultures and in Oxidatively Stressed Human Neurons
por: Ruiz-Perera, Lucia M., et al.
Publicado: (2021)

Targeting NF-κB Signaling in Cancer Stem Cells: A Narrative Review
por: Kaltschmidt, Barbara, et al.
Publicado: (2022)

Transcriptome Analysis Reveals High Similarities between Adult Human Cardiac Stem Cells and Neural Crest-Derived Stem Cells
por: Höving, Anna L., et al.
Publicado: (2020)

Subunit-Specific Role of NF-κB in Cancer
por: Kaltschmidt, Barbara, et al.
Publicado: (2018)

NF-κB in neurodegenerative diseases: Recent evidence from human genetics
por: Kaltschmidt, Barbara, et al.
Publicado: (2022)

Strategies to Improve Bone Healing: Innovative Surgical Implants Meet Nano-/Micro-Topography of Bone Scaffolds
por: Wähnert, Dirk, et al.
Publicado: (2021)

Culture bag systems for clinical applications of adult human neural crest-derived stem cells
por: Greiner, Johannes FW, et al.
Publicado: (2014)

Stem Cell-Induced Inflammation in Cholesteatoma Is Inhibited by the TLR4 Antagonist LPS-RS
por: Schürmann, Matthias, et al.
Publicado: (2020)

Preparation of Terpenoid-Invasomes with Selective Activity against S. aureus and Characterization by Cryo Transmission Electron Microscopy
por: Kaltschmidt, Bernhard P., et al.
Publicado: (2020)

Cyclooxygenase-2 is a neuronal target gene of NF-κB
por: Kaltschmidt, Barbara, et al.
Publicado: (2002)

Human Sex Matters: Y-Linked Lysine Demethylase 5D Drives Accelerated Male Craniofacial Osteogenic Differentiation
por: Merten, Madlen, et al.
Publicado: (2022)

Knockdown of IKK1/2 Promotes Differentiation of Mouse Embryonic Stem Cells into Neuroectoderm at the Expense of Mesoderm
por: Lüningschrör, Patrick, et al.
Publicado: (2012)

Transcription Factor NF-κB Is Transported to the Nucleus via Cytoplasmic Dynein/Dynactin Motor Complex in Hippocampal Neurons
por: Mikenberg, Ilja, et al.
Publicado: (2007)

Stem cells in middle ear cholesteatoma contribute to its pathogenesis
por: Nagel, Julia, et al.
Publicado: (2018)

Origin and Regenerative Potential of Vertebrate Mechanoreceptor-Associated Stem Cells
por: Widera, Darius, et al.
Publicado: (2012)

NF-KappaB in Long-Term Memory and Structural Plasticity in the Adult Mammalian Brain
por: Kaltschmidt, Barbara, et al.
Publicado: (2015)

Human Blood Serum Induces p38-MAPK- and Hsp27-Dependent Migration Dynamics of Adult Human Cardiac Stem Cells: Single-Cell Analysis via a Microfluidic-Based Cultivation Platform
por: Höving, Anna L., et al.
Publicado: (2021)

1,8-Cineol Reduces Mucus-Production in a Novel Human Ex Vivo Model of Late Rhinosinusitis
por: Sudhoff, Holger, et al.
Publicado: (2015)

Label-free nonlinear optical microscopy detects early markers for osteogenic differentiation of human stem cells
por: Hofemeier, Arne D., et al.
Publicado: (2016)

A typical carcinoid of the lung – a case report with pathological correlation and propagation of the cancer stem cell line BKZ1 with synaptophysin expression
por: Windmöller, Beatrice Ariane, et al.
Publicado: (2019)

Improved Method for Ex Ovo-Cultivation of Developing Chicken Embryos for Human Stem Cell Xenografts
por: Schomann, Timo, et al.
Publicado: (2013)

Spongostan(™) Leads to Increased Regeneration of a Rat Calvarial Critical Size Defect Compared to NanoBone(®) and Actifuse
por: Wähnert, Dirk, et al.
Publicado: (2021)

Tumor necrosis factor alpha induced proliferation of adult neural stem cells is mediated via NF-κB
por: Widera, Darius, et al.
Publicado: (2007)

Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/NF-κB signaling
por: Widera, Darius, et al.
Publicado: (2006)

Novel Primary Human Cancer Stem-Like Cell Populations from Non-Small Cell Lung Cancer: Inhibition of Cell Survival by Targeting NF-κB and MYC Signaling
por: Windmöller, Beatrice A., et al.
Publicado: (2021)

Bacterial Biofilm Formation on Nano-Copper Added PLA Suited for 3D Printed Face Masks
por: Kiel, Annika, et al.
Publicado: (2022)

From induction to conduction: how intrinsic transcriptional priming of extrinsic neuronal connectivity shapes neuronal identity
por: Russ, Jeffrey B., et al.
Publicado: (2014)

MoNa – A Cost-Efficient, Portable System for the Nanoinjection of Living Cells
por: Simonis, Matthias, et al.
Publicado: (2019)

Neural stem cells, inflammation and NF-κB: basic principle of maintenance and repair or origin of brain tumours?
por: Widera, D, et al.
Publicado: (2008)

Blood Serum Stimulates p38-Mediated Proliferation and Changes in Global Gene Expression of Adult Human Cardiac Stem Cells
por: Höving, Anna L., et al.
Publicado: (2020)

Targeting Key Signaling Pathways in Glioblastoma Stem Cells for the Development of Efficient Chemo- and Immunotherapy
por: Helweg, Laureen P., et al.
Publicado: (2022)

Hsc70 Is a Novel Interactor of NF-kappaB p65 in Living Hippocampal Neurons
por: Klenke, Christin, et al.
Publicado: (2013)

Technical feasibility study for production of tailored multielectrode arrays and patterning of arranged neuronal networks
por: Schürmann, Matthias, et al.
Publicado: (2018)

Pseudomonas aeruginosa Clusters Toxic Nickel Nanoparticles to Enhance Survival
por: Asghari, Ehsan, et al.
Publicado: (2022)

On the cytotoxicity of HCR-NTPase in the neuroblastoma cell line SH-SY5Y
por: Pasdziernik, Markus, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_pio1psli9fp7jj9j1ntusahqhp