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Changes in the Expression of Pre-Replicative Complex Genes in hTERT and ALT Pediatric Brain Tumors

Background: The up-regulation of a telomere maintenance mechanism (TMM) is a common feature of cancer cells and a hallmark of cancer. Routine methods for detecting TMMs in tumor samples are still missing, whereas telomerase targeting treatments are becoming available. In paediatric cancers, alternat...

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Detalles Bibliográficos
Autores principales: Idilli, Aurora Irene, Pagani, Francesca, Kerschbamer, Emanuela, Berardinelli, Francesco, Bernabé, Manuel, Cayuela, María Luisa, Piazza, Silvano, Poliani, Pietro Luigi, Cusanelli, Emilio, Mione, Maria Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226177/
https://www.ncbi.nlm.nih.gov/pubmed/32331249
http://dx.doi.org/10.3390/cancers12041028