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The Interplay of Dysregulated pH and Electrolyte Imbalance in Cancer
Cancer cells and tissues have an aberrant regulation of hydrogen ion dynamics driven by a combination of poor vascular perfusion, regional hypoxia, and increased the flux of carbons through fermentative glycolysis. This leads to extracellular acidosis and intracellular alkalinization. Dysregulated p...
Autores principales: | Alfarouk, Khalid O., Ahmed, Samrein B. M., Ahmed, Ahmed, Elliott, Robert L., Ibrahim, Muntaser E., Ali, Heyam S., Wales, Christian C., Nourwali, Ibrahim, Aljarbou, Ahmed N., Bashir, Adil H. H., Alhoufie, Sari T. S., Alqahtani, Saad Saeed, Cardone, Rosa A., Fais, Stefano, Harguindey, Salvador, Reshkin, Stephan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226178/ https://www.ncbi.nlm.nih.gov/pubmed/32272658 http://dx.doi.org/10.3390/cancers12040898 |
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