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Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells

Loss of heterozygosity or mutation of the family with sequence similarity 46, member C (FAM46C) gene on chromosome band 1p12 is associated with shorter overall survival of patients with multiple myeloma (MM). In this study, using human MM cell lines (KMS‐11, OCI‐My5, and ANBL‐6), we generated FAM46C...

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Detalles Bibliográficos
Autores principales:	Kanasugi, Jo, Hanamura, Ichiro, Ota, Akinobu, Karnan, Sivasundaram, Lam, Vu Quang, Mizuno, Shohei, Wahiduzzaman, Md, Rahman, Md Lutfur, Hyodo, Toshinori, Konishi, Hiroyuki, Tsuzuki, Shinobu, Hosokawa, Yoshitaka, Takami, Akiyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226186/ https://www.ncbi.nlm.nih.gov/pubmed/32176823 http://dx.doi.org/10.1111/cas.14386

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