Knockdown of UTX/KDM6A Enriches Precursor Cell Populations in Urothelial Cell Cultures and Cell Lines

The histone demethylase UTX (gene: KDM6A) directs cell and tissue differentiation during development. Deleterious mutations in KDM6A occur in many human cancers, most frequently in urothelial carcinoma. The consequences of these mutations are poorly understood; plausibly, they may disturb urothelial...

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Detalles Bibliográficos
Autores principales: Lang, Alexander, Whongsiri, Patcharawalai, Yilmaz, Merve, Lautwein, Tobias, Petzsch, Patrick, Greife, Annemarie, Günes, Cagatay, Köhrer, Karl, Niegisch, Günter, Hoffmann, Michèle, Schulz, Wolfgang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226239/
https://www.ncbi.nlm.nih.gov/pubmed/32326336
http://dx.doi.org/10.3390/cancers12041023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226239/
https://www.ncbi.nlm.nih.gov/pubmed/32326336
http://dx.doi.org/10.3390/cancers12041023

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