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Chromosome Instability; Implications in Cancer Development, Progression, and Clinical Outcomes
Chromosome instability (CIN) refers to an ongoing rate of chromosomal changes and is a driver of genetic, cell-to-cell heterogeneity. It is an aberrant phenotype that is intimately associated with cancer development and progression. The presence, extent, and level of CIN has tremendous implications...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226245/ https://www.ncbi.nlm.nih.gov/pubmed/32235397 http://dx.doi.org/10.3390/cancers12040824 |