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TIE2 Induces Breast Cancer Cell Dormancy and Inhibits the Development of Osteolytic Bone Metastases

Breast cancer (BCa) cells disseminating to the bone can remain dormant and resistant to treatments for many years until relapsing as bone metastases. The tyrosine kinase receptor TIE2 induces the dormancy of hematopoietic stem cells, and could also induce the dormancy of BCa cells. However, TIE2 is...

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Detalles Bibliográficos
Autores principales: Drescher, Florian, Juárez, Patricia, Arellano, Danna L., Serafín-Higuera, Nicolás, Olvera-Rodriguez, Felipe, Jiménez, Samanta, Licea-Navarro, Alexei F., Fournier, Pierrick G.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226250/
https://www.ncbi.nlm.nih.gov/pubmed/32260072
http://dx.doi.org/10.3390/cancers12040868

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