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Antitumor activity of a novel oral signal transducer and activator of transcription 3 inhibitor YHO‐1701

The signal transducer and activator of transcription 3 (STAT3) signaling pathway is a key mediator of cancer cell proliferation, survival and invasion. Aberrant STAT3 has been demonstrated in various malignant cancers. YHO‐1701 is a novel quinolinecarboxamide derivative generated from STX‐0119. Here...

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Detalles Bibliográficos
Autores principales: Nishisaka, Fukiko, Taniguchi, Keisuke, Tsugane, Momomi, Hirata, Genya, Takagi, Akimitsu, Asakawa, Naoyuki, Kurita, Akinobu, Takahashi, Hiroyuki, Ogo, Naohisa, Shishido, Yoshiyuki, Asai, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226286/
https://www.ncbi.nlm.nih.gov/pubmed/32112605
http://dx.doi.org/10.1111/cas.14369