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Antiproliferative and Antimigration Activities of Fluoro-Neplanocin A via Inhibition of Histone H3 Methylation in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is among the most aggressive and potentially metastatic malignancies. Most affected patients have poor clinical outcomes due to the lack of specific molecular targets on tumor cells. The upregulated expression of disruptor of telomeric silencing 1-like (DOT1L), a...

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Detalles Bibliográficos
Autores principales: Byun, Woong Sub, Kim, Won Kyung, Yoon, Ji-seong, Jarhad, Dnyandev B., Jeong, Lak Shin, Lee, Sang Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226301/
https://www.ncbi.nlm.nih.gov/pubmed/32244385
http://dx.doi.org/10.3390/biom10040530