Iron Oxide Nanoparticle-Induced Autophagic Flux Is Regulated by Interplay between p53-mTOR Axis and Bcl-2 Signaling in Hepatic Cells

Iron oxide-based nanoparticles have been repeatedly shown to affect lysosomal-mediated signaling. Recently, nanoparticles have demonstrated an ability to modulate autophagic flux via lysosome-dependent signaling. However, the precise underlying mechanisms of such modulation as well as the impact of...

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Detalles Bibliográficos
Autores principales: Uzhytchak, Mariia, Smolková, Barbora, Lunova, Mariia, Jirsa, Milan, Frtús, Adam, Kubinová, Šárka, Dejneka, Alexandr, Lunov, Oleg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226334/
https://www.ncbi.nlm.nih.gov/pubmed/32325714
http://dx.doi.org/10.3390/cells9041015

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