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Role of CYP3A5 in Modulating Androgen Receptor Signaling and Its Relevance to African American Men with Prostate Cancer

Androgen receptor signaling is crucial for prostate cancer growth and is positively regulated in part by intratumoral CYP3A5. As African American (AA) men often carry the wild type CYP3A5 and express high levels of CYP3A5 protein, we blocked the wild type CYP3A5 in AA origin prostate cancer cells an...

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Detalles Bibliográficos
Autores principales:	Gorjala, Priyatham, Kittles, Rick A., Goodman Jr., Oscar B., Mitra, Ranjana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226359/ https://www.ncbi.nlm.nih.gov/pubmed/32316460 http://dx.doi.org/10.3390/cancers12040989

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