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Early Response to the Plant Toxin Stenodactylin in Acute Myeloid Leukemia Cells Involves Inflammatory and Apoptotic Signaling
Stenodactylin, a highly toxic type 2 ribosome-inactivating protein purified from the caudex of Adenia stenodactyla Harms, is a potential anticancer drug candidate. Previous studies demonstrated that stenodactylin induces apoptosis and necroptosis in treated cells, involving the production of reactiv...
Autores principales: | Mercatelli, Daniele, Bortolotti, Massimo, Andresen, Vibeke, Sulen, André, Polito, Letizia, Gjertsen, Bjørn Tore, Bolognesi, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226368/ https://www.ncbi.nlm.nih.gov/pubmed/32457623 http://dx.doi.org/10.3389/fphar.2020.00630 |
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