Role of DNA Damage Response in Suppressing Malignant Progression of Chronic Myeloid Leukemia and Polycythemia Vera: Impact of Different Oncogenes

Inflammatory and oncogenic signaling, both known to challenge genome stability, are key drivers of BCR-ABL-positive chronic myeloid leukemia (CML) and JAK2 V617F-positive chronic myeloproliferative neoplasms (MPNs). Despite similarities in chronic inflammation and oncogene signaling, major differenc...

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Detalles Bibliográficos
Autores principales: Stetka, Jan, Gursky, Jan, Liñan Velasquez, Julie, Mojzikova, Renata, Vyhlidalova, Pavla, Vrablova, Lucia, Bartek, Jiri, Divoky, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226398/
https://www.ncbi.nlm.nih.gov/pubmed/32272770
http://dx.doi.org/10.3390/cancers12040903

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