Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization

Rational drug design and in vitro pharmacology profiling constitute the gold standard in drug development pipelines. Problems arise, however, because this process is often difficult due to limited information regarding the complete identification of a molecule’s biological activities. The increasing...

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Detalles Bibliográficos
Autores principales: Króliczewski, Jarosław, Bartoszewska, Sylwia, Dudkowska, Magdalena, Janiszewska, Dorota, Biernatowska, Agnieszka, Crossman, David K., Krzymiński, Karol, Wysocka, Małgorzata, Romanowska, Anna, Baginski, Maciej, Markuszewski, Michal, Ochocka, Renata J., Collawn, James F., Sikorski, Aleksander F., Sikora, Ewa, Bartoszewski, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226417/
https://www.ncbi.nlm.nih.gov/pubmed/32252403
http://dx.doi.org/10.3390/cancers12040864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226417/
https://www.ncbi.nlm.nih.gov/pubmed/32252403
http://dx.doi.org/10.3390/cancers12040864

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