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Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization
Rational drug design and in vitro pharmacology profiling constitute the gold standard in drug development pipelines. Problems arise, however, because this process is often difficult due to limited information regarding the complete identification of a molecule’s biological activities. The increasing...
Autores principales: | Króliczewski, Jarosław, Bartoszewska, Sylwia, Dudkowska, Magdalena, Janiszewska, Dorota, Biernatowska, Agnieszka, Crossman, David K., Krzymiński, Karol, Wysocka, Małgorzata, Romanowska, Anna, Baginski, Maciej, Markuszewski, Michal, Ochocka, Renata J., Collawn, James F., Sikorski, Aleksander F., Sikora, Ewa, Bartoszewski, Rafal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226417/ https://www.ncbi.nlm.nih.gov/pubmed/32252403 http://dx.doi.org/10.3390/cancers12040864 |
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