Cargando…

Discoidin Domain Receptor-1 (DDR1) is Involved in Angiolymphatic Invasion in Oral Cancer

The discoidin domain receptor-1 (DDR1) is a non-integrin collagen receptor recently implicated in the collective cell migration of other cancer types. Previously, we identified an elevated expression of DDR1 in oral squamous cell carcinoma (OSCC) cells. Through the data mining of a microarray datase...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yu-Lian, Tsai, Wan-Hua, Ko, Ying-Chieh, Lai, Ting-Yu, Cheng, Ann-Joy, Shiah, Shine-Gwo, Hsiao, Jenn-Ren, Chang, Jang-Yang, Lin, Su-Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226486/ https://www.ncbi.nlm.nih.gov/pubmed/32244515 http://dx.doi.org/10.3390/cancers12040841

Ejemplares similares

Inhibitors of Discoidin Domain Receptor (DDR) Kinases for Cancer and Inflammation
por: Denny, William A., et al.
Publicado: (2021)

Periostin interaction with discoidin domain receptor-1 (DDR1) promotes cartilage degeneration
por: Han, Tianzhen, et al.
Publicado: (2020)

Expression and subcellular localization of Discoidin Domain Receptor 1 (DDR1) define prostate cancer aggressiveness
por: Bonfil, R. Daniel, et al.
Publicado: (2021)

Glycosylation at Asn(211) Regulates the Activation State of the Discoidin Domain Receptor 1 (DDR1)
por: Fu, Hsueh-Liang, et al.
Publicado: (2014)

MicroRNA-486-3p functions as a tumor suppressor in oral cancer by targeting DDR1
por: Chou, Sung-Tau, et al.
Publicado: (2019)

Discoidin Domain Receptors, DDR1b and DDR2, Promote Tumour Growth within Collagen but DDR1b Suppresses Experimental Lung Metastasis in HT1080 Xenografts
por: Wasinski, Benjamin, et al.
Publicado: (2020)

Exploring the Cellular and Molecular Mechanism of Discoidin Domain Receptors (DDR1 and DDR2) in Bone Formation, Regeneration, and Its Associated Disease Conditions
por: Mariadoss, Arokia Vijaya Anand, et al.
Publicado: (2023)

Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors
por: Wang, Zhen, et al.
Publicado: (2016)

Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix‐mediated tumor cell adaptation and tolerance to BRAF‐targeted therapy in melanoma
por: Berestjuk, Ilona, et al.
Publicado: (2021)

Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric Cancer()
por: Yuge, Ryo, et al.
Publicado: (2018)

TWIST1 induces expression of Discoidin Domain Receptor2 (DDR2) to Promote Ovarian Cancer Metastasis
por: Grither, Whitney R., et al.
Publicado: (2018)

Identification of Receptor Tyrosine Kinase, Discoidin Domain Receptor 1 (DDR1), as a Potential Biomarker for Serous Ovarian Cancer
por: Quan, Jinhua, et al.
Publicado: (2011)

ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1)
por: Shitomi, Yasuyuki, et al.
Publicado: (2015)

Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers
por: Takai, Ken, et al.
Publicado: (2018)

Discoidin Domain Receptor Tyrosine Kinase 1 (DDR1): A Novel Predictor for Recurrence of Hepatocellular Carcinoma After Curative Resection
por: Xu, Meng, et al.
Publicado: (2021)

The tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis
por: Carracedo, Miguel, et al.
Publicado: (2022)

Evaluation of discoidin domain receptor-2 (DDR2) expression level in normal, benign, and malignant human prostate tissues
por: Azemikhah, Mitra, et al.
Publicado: (2015)

Spatial localisation of Discoidin Domain Receptor 2 (DDR2) signalling is dependent on its collagen binding and kinase activity
por: Luczynski, Maciej T., et al.
Publicado: (2018)

Expression and regulation of discoidin domain receptor 1 (DDR1) – a novel receptor for collagen – in normal human renal cells and patients with lupus nephritis
por: Boumpas, DT, et al.
Publicado: (2003)

Discoidin Domain Receptor 1 (DDR1) tyrosine kinase is upregulated in PKD kidneys but does not play a role in the pathogenesis of polycystic kidney disease
por: Soomro, Irfana, et al.
Publicado: (2019)

Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1
por: Xu, Huifang, et al.
Publicado: (2011)

Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease
por: Stevenson, Max, et al.
Publicado: (2023)

Prevalence of Mutations in Discoidin Domain-Containing Receptor Tyrosine Kinase 2 (DDR2) in Squamous Cell Lung Cancers in Korean Patients
por: Lee, Mi-Sook, et al.
Publicado: (2017)

DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular Calcification
por: Ngai, David, et al.
Publicado: (2020)

The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK–JNK Signaling Pathway in Axon Regeneration
por: Hisamoto, Naoki, et al.
Publicado: (2016)

Identification of novel driver mutations of the discoidin domain receptor 2 (DDR2) gene in squamous cell lung cancer of Chinese patients
por: Miao, Liyun, et al.
Publicado: (2014)

Abnormal Accumulation of Collagen Type I Due to the Loss of Discoidin Domain Receptor 2 (Ddr2) Promotes Testicular Interstitial Dysfunction
por: Zhu, Chu-chao, et al.
Publicado: (2015)

Identification of Prognostic Biomarkers Originating From the Tumor Stroma of Betel Quid-Associated Oral Cancer Tissues
por: Liu, Yi-Hong, et al.
Publicado: (2021)

Discoidin domain receptor 1a (DDR1a) confers 5-fluorouracil cytotoxicity in LoVo cell via PI3K/AKT/Bcl-2 pathway
por: Xiong, Bin, et al.
Publicado: (2022)

2-Amino-2,3-dihydro-1H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy
por: Zhu, Dongsheng, et al.
Publicado: (2019)

Targeting Discoidin Domain Receptor 1 (DDR1) Signaling and Its Crosstalk with β(1)-Integrin Emerges as a Key Factor for Breast Cancer Chemosensitization upon Collagen Type 1 Binding
por: Baltes, Fabian, et al.
Publicado: (2020)

Recent Advances in the Role of Discoidin Domain Receptor Tyrosine Kinase 1 and Discoidin Domain Receptor Tyrosine Kinase 2 in Breast and Ovarian Cancer
por: Chen, Li, et al.
Publicado: (2021)

IL‐8 induces miR‐424‐5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinoma
por: Peng, Hsuan-Yu, et al.
Publicado: (2016)

TNF-α-induced miR-450a mediates TMEM182 expression to promote oral squamous cell carcinoma motility
por: Hsing, En-Wei, et al.
Publicado: (2019)

MiR-944/CISH mediated inflammation via STAT3 is involved in oral cancer malignance by cigarette smoking
por: Peng, Hsuan-Yu, et al.
Publicado: (2020)

Regulation of c-Fos Gene Expression by NF-κB: A p65 Homodimer Binding Site in Mouse Embryonic Fibroblasts but Not Human HEK293 Cells
por: Tu, Yu-Cheng, et al.
Publicado: (2013)

MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer
por: Shiah, Shine-Gwo, et al.
Publicado: (2020)

Angiolymphatic invasion as a prognostic fator in resected N0 pancreatic adenocarcinoma
por: de ALMEIDA, Ricardo Vitor Silva, et al.
Publicado: (2017)

Reciprocal regulation of MicroRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells
por: Yen, Yi-Chen, et al.
Publicado: (2014)

Discoidin Domain Receptor 1 Contributes to Tumorigenesis through Modulation of TGFBI Expression
por: Rudra-Ganguly, Nandini, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2l3l6n1kj06clvca51vnvvlc11