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Recent Synthetic Approaches towards Small Molecule Reactivators of p53
The tumor suppressor protein p53 is often called “the genome guardian” and controls the cell cycle and the integrity of DNA, as well as other important cellular functions. Its main function is to trigger the process of apoptosis in tumor cells, and approximately 50% of all cancers are related to the...
Autores principales: | Silva, Jerson L., Lima, Carolina G. S., Rangel, Luciana P., Ferretti, Giulia D. S., Pauli, Fernanda P., Ribeiro, Ruan C. B., da Silva, Thais de B., da Silva, Fernando C., Ferreira, Vitor F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226499/ https://www.ncbi.nlm.nih.gov/pubmed/32326087 http://dx.doi.org/10.3390/biom10040635 |
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