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Potency and Selectivity of SMAC/DIABLO Mimetics in Solid Tumor Therapy

Aiming to promote cancer cell apoptosis is a mainstream strategy of cancer therapy. The second mitochondria-derived activator of caspase (SMAC)/direct inhibitor of apoptosis protein (IAP)-binding protein with low pI (DIABLO) protein is an essential and endogenous antagonist of inhibitor of apoptosis...

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Detalles Bibliográficos
Autores principales: Zhao, Xiao-Yun, Wang, Xiu-Yun, Wei, Qi-Yao, Xu, Yan-Ming, Lau, Andy T. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226512/
https://www.ncbi.nlm.nih.gov/pubmed/32325691
http://dx.doi.org/10.3390/cells9041012

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