Secondary Resistant Mutations to Small Molecule Inhibitors in Cancer Cells

Secondary resistant mutations in cancer cells arise in response to certain small molecule inhibitors. These mutations inevitably cause recurrence and often progression to a more aggressive form. Resistant mutations may manifest in various forms. For example, some mutations decrease or abrogate the a...

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Detalles Bibliográficos
Autores principales: Hamid, Abdulaziz B., Petreaca, Ruben C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226513/
https://www.ncbi.nlm.nih.gov/pubmed/32283832
http://dx.doi.org/10.3390/cancers12040927

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