Frequent FOXA1-Activating Mutations in Extramammary Paget’s Disease

Extramammary Paget’s disease (EMPD) is a neoplastic skin disease of indeterminate origin with an unknown genetic cause. We performed a comprehensive genetic analysis or targeted gene sequencing in 48 patients with EMPD. We identified FOXA1 mutations, a GAS6–FOXA1 fusion gene, and somatic hotspot mut...

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Detalles Bibliográficos
Autores principales: Takeichi, Takuya, Okuno, Yusuke, Matsumoto, Takaaki, Tsunoda, Nobuyuki, Suzuki, Kyogo, Tanahashi, Kana, Kono, Michihiro, Kikumori, Toyone, Muro, Yoshinao, Akiyama, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226542/
https://www.ncbi.nlm.nih.gov/pubmed/32235312
http://dx.doi.org/10.3390/cancers12040820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226542/
https://www.ncbi.nlm.nih.gov/pubmed/32235312
http://dx.doi.org/10.3390/cancers12040820

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