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Genetic association of polymorphism rs2230054 in CXCR2 gene with gout in Chinese Han male population
Neutrophils are crucial in the process of gout flare and remission. The signal transduction pathway of chemokine plays a vital role in the chemotaxis and activation of neutrophils. CXCR2 gene knocked out can avoid the acute neutrophilic inflammation stimulated by monosodium urate (MSU) crystals in m...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226559/ https://www.ncbi.nlm.nih.gov/pubmed/32425684 http://dx.doi.org/10.5114/ceji.2020.94702 |