Cargando…

Extracellular Vesicles isolated from Mesenchymal Stromal Cells Modulate CD4(+) T Lymphocytes Toward a Regulatory Profile

Mesenchymal stromal cells (MSCs) can generate immunological tolerance due to their regulatory activity in many immune cells. Extracellular vesicles (EVs) release is a pivotal mechanism by which MSCs exert their actions. In this study, we evaluate whether mesenchymal stromal cell extracellular vesicl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Franco da Cunha, Flavia, Andrade-Oliveira, Vinicius, Candido de Almeida, Danilo, Borges da Silva, Tamiris, Naffah de Souza Breda, Cristiane, Costa Cruz, Mario, Faquim-Mauro, Eliana L., Antonio Cenedeze, Marcos, Ioshie Hiyane, Meire, Pacheco-Silva, Alvaro, Aparecida Cavinato, Regiane, Torrecilhas, Ana Claudia, Olsen Saraiva Câmara, Niels
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226573/ https://www.ncbi.nlm.nih.gov/pubmed/32340348 http://dx.doi.org/10.3390/cells9041059

Ejemplares similares

Adipose Tissue-Derived Stem Cells Reduce Acute and Chronic Kidney Damage in Mice
por: Burgos-Silva, Marina, et al.
Publicado: (2015)

Increased lacrimal inflammatory mediators in patients with keratoconus
por: Moura, Gustavo Souza, et al.
Publicado: (2021)

A Regulatory miRNA–mRNA Network Is Associated with Tissue Repair Induced by Mesenchymal Stromal Cells in Acute Kidney Injury
por: de Almeida, Danilo Candido, et al.
Publicado: (2017)

The dual effect of acetate on microglial TNF-α production
por: Fragas, Matheus Garcia, et al.
Publicado: (2022)

Butyrate Attenuates Lung Inflammation by Negatively Modulating Th9 Cells
por: Vieira, Raquel de Souza, et al.
Publicado: (2019)

Innate lymphoid cells in tissue homeostasis and diseases
por: Ignacio, Aline, et al.
Publicado: (2017)

Macrophage Trafficking as Key Mediator of Adenine-Induced Kidney Injury
por: Correa-Costa, Matheus, et al.
Publicado: (2014)

TLR2, TLR4 and the MYD88 Signaling Pathway Are Crucial for Neutrophil Migration in Acute Kidney Injury Induced by Sepsis
por: Castoldi, Angela, et al.
Publicado: (2012)

Transcriptome Analysis of Renal Ischemia/Reperfusion Injury and Its Modulation by Ischemic Pre-Conditioning or Hemin Treatment
por: Correa-Costa, Matheus, et al.
Publicado: (2012)

Long-Term Aerobic Exercise Protects against Cisplatin-Induced Nephrotoxicity by Modulating the Expression of IL-6 and HO-1
por: Miyagi, Mariana Yasue Saito, et al.
Publicado: (2014)

Antibody Profile Comparison against MSP1 Antigens of Multiple Plasmodium Species in Human Serum Samples from Two Different Brazilian Populations Using a Multiplex Serological Assay
por: Monteiro, Eliana Ferreira, et al.
Publicado: (2021)

Balance between the two kinin receptors in the progression of experimental focal and segmental glomerulosclerosis in mice
por: Pereira, Rafael Luiz, et al.
Publicado: (2014)

Mitochondria as central hub of the immune system
por: Breda, Cristiane Naffah de Souza, et al.
Publicado: (2019)

The role of dexamethasone in scorpion venom-induced deregulation of sodium and water transport in rat lungs
por: Malaque, Ceila Maria Sant Ana, et al.
Publicado: (2015)

Mesenchymal Stromal Cell-Derived Microvesicles Regulate an Internal Pro-Inflammatory Program in Activated Macrophages
por: Henao Agudelo, Juan S., et al.
Publicado: (2017)

Crotoxin from Crotalus durissus terrificus Is Able to Down-Modulate the Acute Intestinal Inflammation in Mice
por: Almeida, Caroline de Souza, et al.
Publicado: (2015)

Transcriptome analysis of six tissues obtained post‐mortem from sepsis patients
por: Pinheiro da Silva, Fabiano, et al.
Publicado: (2023)

Alkaline pH Promotes NADPH Oxidase-Independent Neutrophil Extracellular Trap Formation: A Matter of Mitochondrial Reactive Oxygen Species Generation and Citrullination and Cleavage of Histone
por: Naffah de Souza, Cristiane, et al.
Publicado: (2018)

The Macrophage Switch in Obesity Development
por: Castoldi, Angela, et al.
Publicado: (2016)

Interference of natural mouse hepatitis virus infection with cytokine production and susceptibility to Trypanosoma cruzi
por: Torrecilhas, A C T, et al.
Publicado: (1999)

Different wild type strains of zebrafish show divergent susceptibility to TNBS-induced intestinal inflammation displaying distinct immune cell profiles
por: Padovani, Barbara Nunes, et al.
Publicado: (2022)

Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development
por: Braga, Tarcio Teodoro, et al.
Publicado: (2016)

Soluble Uric Acid Activates the NLRP3 Inflammasome
por: Braga, Tarcio Teodoro, et al.
Publicado: (2017)

Adipose Tissue-Derived Mesenchymal Stem Cells Increase Skin Allograft Survival and Inhibit Th-17 Immune Response
por: Larocca, Rafael Assumpção, et al.
Publicado: (2013)

Exercise during pregnancy protects adult mouse offspring from diet-induced obesity
por: Wasinski, Frederick, et al.
Publicado: (2015)

Host dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity
por: Almeida, Rafael Ribeiro, et al.
Publicado: (2020)

Fonsecaea pedrosoi Conidia and Hyphae Activate Neutrophils Distinctly: Requirement of TLR-2 and TLR-4 in Neutrophil Effector Functions
por: Breda, Leandro Carvalho Dantas, et al.
Publicado: (2020)

Role of aryl hydrocarbon receptor in mesenchymal stromal cell activation: A minireview
por: de Almeida, Danilo Candido, et al.
Publicado: (2017)

Sensing soluble uric acid by Naip1-Nlrp3 platform
por: Braga, Tarcio Teodoro, et al.
Publicado: (2021)

Intragraft transcriptional profiling of renal transplant patients with tubular dysfunction reveals mechanisms underlying graft injury and recovery
por: Azevedo, Hátylas, et al.
Publicado: (2016)

Oxidative Stress and Modification of Renal Vascular Permeability Are Associated with Acute Kidney Injury during P. berghei ANKA Infection
por: Elias, Rosa Maria, et al.
Publicado: (2012)

Acute effects of power and resistance exercises on hemodynamic measurements of older women
por: Coelho-Júnior, Hélio José, et al.
Publicado: (2017)

Immune Regulatory Properties of Allogeneic Adipose-Derived Mesenchymal Stem Cells in the Treatment of Experimental Autoimmune Diabetes
por: Bassi, Ênio J., et al.
Publicado: (2012)

CD28 deficiency leads to accumulation of germinal-center independent IgM(+) experienced B cells and to production of protective IgM during experimental malaria
por: Borges da Silva, Henrique, et al.
Publicado: (2018)

Correction: CD28 deficiency leads to accumulation of germinal-center independent IgM(+) experienced B cells and to production of protective IgM during experimental malaria
por: Borges da Silva, Henrique, et al.
Publicado: (2019)

Comparative photoelastic study of dental and skeletal anchorages in the canine retraction
por: Claro, Cristiane Aparecida de Assis, et al.
Publicado: (2014)

Pivotal Role of Toll-Like Receptors 2 and 4, Its Adaptor Molecule MyD88, and Inflammasome Complex in Experimental Tubule-Interstitial Nephritis
por: Correa-Costa, Matheus, et al.
Publicado: (2011)

Inflammatory Reaction Induced by Two Metalloproteinases Isolated from Bothrops atrox Venom and by Fragments Generated from the Hydrolysis of Basement Membrane Components
por: de Almeida, Michelle Teixeira, et al.
Publicado: (2020)

P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis
por: de Salles, Érika Machado, et al.
Publicado: (2023)

Neutrophil-suppressive activity over T-cell proliferation and fungal clearance in a murine model of Fonsecaea pedrosoi infection
por: Breda, Leandro Carvalho Dantas, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qjg7257r5qui6ienko4cu5adab