Functional and Clinical Impact of CircRNAs in Oral Cancer

The increasing number of recently published works regarding the role of circular RNAs (circRNAs) in oral cancer highlights the key contribution of this novel class of endogenous noncoding RNAs as regulators of critical signaling pathways and their clinical value as novel biomarkers. This review summ...

Descripción completa

Detalles Bibliográficos
Autores principales: Cristóbal, Ion, Caramés, Cristina, Rubio, Jaime, Sanz-Alvarez, Marta, Luque, Melani, Madoz-Gúrpide, Juan, Rojo, Federico, García-Foncillas, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226580/
https://www.ncbi.nlm.nih.gov/pubmed/32340253
http://dx.doi.org/10.3390/cancers12041041
Descripción
Sumario:The increasing number of recently published works regarding the role of circular RNAs (circRNAs) in oral cancer highlights the key contribution of this novel class of endogenous noncoding RNAs as regulators of critical signaling pathways and their clinical value as novel biomarkers. This review summarizes and puts into context the existing literature in order to clarify the relevance of circRNAs as novel mediators of oral cancer pathogenesis as well as their potential usefulness as predictors of clinical outcome and response to therapy in this disease.

Ejemplares similares