Functional and Clinical Impact of CircRNAs in Oral Cancer

The increasing number of recently published works regarding the role of circular RNAs (circRNAs) in oral cancer highlights the key contribution of this novel class of endogenous noncoding RNAs as regulators of critical signaling pathways and their clinical value as novel biomarkers. This review summ...

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Autores principales: Cristóbal, Ion, Caramés, Cristina, Rubio, Jaime, Sanz-Alvarez, Marta, Luque, Melani, Madoz-Gúrpide, Juan, Rojo, Federico, García-Foncillas, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226580/
https://www.ncbi.nlm.nih.gov/pubmed/32340253
http://dx.doi.org/10.3390/cancers12041041
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author Cristóbal, Ion
Caramés, Cristina
Rubio, Jaime
Sanz-Alvarez, Marta
Luque, Melani
Madoz-Gúrpide, Juan
Rojo, Federico
García-Foncillas, Jesús
author_facet Cristóbal, Ion
Caramés, Cristina
Rubio, Jaime
Sanz-Alvarez, Marta
Luque, Melani
Madoz-Gúrpide, Juan
Rojo, Federico
García-Foncillas, Jesús
author_sort Cristóbal, Ion
collection PubMed
description The increasing number of recently published works regarding the role of circular RNAs (circRNAs) in oral cancer highlights the key contribution of this novel class of endogenous noncoding RNAs as regulators of critical signaling pathways and their clinical value as novel biomarkers. This review summarizes and puts into context the existing literature in order to clarify the relevance of circRNAs as novel mediators of oral cancer pathogenesis as well as their potential usefulness as predictors of clinical outcome and response to therapy in this disease.
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spelling pubmed-72265802020-05-18 Functional and Clinical Impact of CircRNAs in Oral Cancer Cristóbal, Ion Caramés, Cristina Rubio, Jaime Sanz-Alvarez, Marta Luque, Melani Madoz-Gúrpide, Juan Rojo, Federico García-Foncillas, Jesús Cancers (Basel) Review The increasing number of recently published works regarding the role of circular RNAs (circRNAs) in oral cancer highlights the key contribution of this novel class of endogenous noncoding RNAs as regulators of critical signaling pathways and their clinical value as novel biomarkers. This review summarizes and puts into context the existing literature in order to clarify the relevance of circRNAs as novel mediators of oral cancer pathogenesis as well as their potential usefulness as predictors of clinical outcome and response to therapy in this disease. MDPI 2020-04-23 /pmc/articles/PMC7226580/ /pubmed/32340253 http://dx.doi.org/10.3390/cancers12041041 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Cristóbal, Ion
Caramés, Cristina
Rubio, Jaime
Sanz-Alvarez, Marta
Luque, Melani
Madoz-Gúrpide, Juan
Rojo, Federico
García-Foncillas, Jesús
Functional and Clinical Impact of CircRNAs in Oral Cancer
title Functional and Clinical Impact of CircRNAs in Oral Cancer
title_full Functional and Clinical Impact of CircRNAs in Oral Cancer
title_fullStr Functional and Clinical Impact of CircRNAs in Oral Cancer
title_full_unstemmed Functional and Clinical Impact of CircRNAs in Oral Cancer
title_short Functional and Clinical Impact of CircRNAs in Oral Cancer
title_sort functional and clinical impact of circrnas in oral cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226580/
https://www.ncbi.nlm.nih.gov/pubmed/32340253
http://dx.doi.org/10.3390/cancers12041041
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